| Product Number |
ARP38600_T100 |
| Product Page |
www.avivasysbio.com/hcfc1-antibody-n-terminal-region-arp38600-t100.html |
| Name |
HCFC1 Antibody - N-terminal region (ARP38600_T100) |
| Protein Size (# AA) |
428 amino acids |
| Molecular Weight |
45kDa |
| NCBI Gene Id |
3054 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
1.0 mg/ml |
| Gene Full Name |
Host cell factor C1 (VP16-accessory protein) |
| Alias Symbols |
CFF, HCF, HCF1, HFC1, MRX3, VCAF, HCF-1, PPP1R89 |
| Peptide Sequence |
Synthetic peptide located within the following region: GTRLLVFGGMVEYGKYSNDLYELQASRWEWKRLKAKTPKNGPPPCPRLGH |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Director MGC Project, (2003) Direct Submission |
| Description of Target |
HCFC1 is a member of the host cell factor family with five Kelch repeats, a fibronectin-like motif, and six HCF repeats, each of which contains a highly specific cleavage signal. This nuclear coactivator is proteolytically cleaved at one of the six possible sites, resulting in the creation of an N-terminal chain and the corresponding C-terminal chain. The final form of this protein consists of noncovalently bound N- and C-terminal chains. The protein is involved in control of the cell cycle and transcriptional regulation during herpes simplex virus infection. |
| Protein Interactions |
FBXW11; BAP1; NUDCD3; CREB3; UBC; RPA3; RPA2; RPA1; EED; EEF1D; CREBZF; LMNA; OGT; POU2F1; NOTCH1; UL48; RBBP5; PPP1CB; PPP1CA; DPY30; WDR5; MAP3K7; HCFC1; EGFR; CLP1; YEATS2; CDK2; CUL3; USF1; NR2C1; THAP11; SIRT7; ELAVL1; SUMO2; ASH2L; SNRPN; SNRPB; YY1 |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-HCFC1 (ARP38600_T100) antibody |
| Blocking Peptide |
For anti-HCFC1 (ARP38600_T100) antibody is Catalog # AAP38600 (Previous Catalog # AAPS04501) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human HCFC1 |
| Uniprot ID |
P51610-3 |
| Protein Name |
Host cell factor 1 |
| Sample Type Confirmation |
HCFC1 is strongly supported by BioGPS gene expression data to be expressed in HepG2 |
| Protein Accession # |
AAH63435 |
| Purification |
Protein A purified |
| Nucleotide Accession # |
NM_005334 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
HCFC1 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 92% |
| Image 1 | transformed bacteria
 | Lanes:
Lane1: HIS-HCFC1 16-363aa (42kD) transformed bacteria lysate
Lane2: GFP-HCFC1 363-2002aa (73kD) transformed bacteria lysate elution sample
Primary Antibody Dilution:
1:1000
Secondary Antibody:
Anti-rabbit AlexaFluor 680
Secondary Antibody Dilution:
1:10000
Gene Name:
HCFC1
Submitted by:
Anonymous
|
|
| Image 2 | Human HepG2
 | WB Suggested Anti-HCFC1 Antibody Titration: 1.25ug/ml
Positive Control: HepG2 cell lysateHCFC1 is strongly supported by BioGPS gene expression data to be expressed in Human HepG2 cells |
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