Product Number |
ARP38589_T100 |
Product Page |
www.avivasysbio.com/elk1-antibody-n-terminal-region-arp38589-t100.html |
Name |
ELK1 Antibody - N-terminal region (ARP38589_T100) |
Protein Size (# AA) |
428 amino acids |
Molecular Weight |
45kDa |
NCBI Gene Id |
2002 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
1.0 mg/ml |
Gene Full Name |
ELK1, member of ETS oncogene family |
Peptide Sequence |
Synthetic peptide located within the following region: MDPSVTLWQFLLQLLREQGNGHIISWTSRDGGEFKLVDAEEVARLWGLRK |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reference |
Hsieh,Y.H., et al., (2006) Biochem. Biophys. Res. Commun. 339 (1), 217-225 |
Description of Target |
ELK1 is a member of the Ets family of transcription factors and of the ternary complex factor (TCF) subfamily. Proteins of the TCF subfamily form a ternary complex by binding to the the serum response factor and the serum reponse element in the promoter of the c-fos proto-oncogene. ELK1 is a nuclear target for the ras-raf-MAPK signaling cascade.This gene is a member of the Ets family of transcription factors and of the ternary complex factor (TCF) subfamily. Proteins of the TCF subfamily form a ternary complex by binding to the the serum response factor and the serum reponse element in the promoter of the c-fos proto-oncogene. The protein encoded by this gene is a nuclear target for the ras-raf-MAPK signaling cascade. |
Protein Interactions |
SUMO1; UBE2I; FBXO25; UBC; SRF; ELK1; MAPK3; MAPK1; STARD3NL; MAPK9; MAPK8; CDK6; MAPK10; APP; SNCA; MAD2L2; PADI4; ELAVL1; Sin3a; HDAC1; HOXB13; KLF4; EMX1; TAOK2; MOB4; ID1; PIAS2; STK16; MAPK11; EP300; MAP2K3; GRB10; ID2; MAPK14; ID3; CREBBP; CEBPB; MA |
Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Datasheets/Manuals |
Printable datasheet for anti-ELK1 (ARP38589_T100) antibody |
Blocking Peptide |
For anti-ELK1 (ARP38589_T100) antibody is Catalog # AAP38589 (Previous Catalog # AAPP20779) |
Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human ELK1 |
Uniprot ID |
P19419 |
Protein Name |
ETS domain-containing protein Elk-1 |
Sample Type Confirmation |
ELK1 is strongly supported by BioGPS gene expression data to be expressed in Jurkat |
Protein Accession # |
NP_005220 |
Purification |
Protein A purified |
Nucleotide Accession # |
NM_005229 |
Tested Species Reactivity |
Human |
Gene Symbol |
ELK1 |
Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit |
Application |
IHC, WB |
Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100% |
Image 1 | Human Placenta
| Rabbit Anti-ELK1 antibody Catalog Number: ARP38589_T100 Paraffin Embedded Tissue: Human Placenta cell Cellular Data: Epithelial cells of renal tubule Antibody Concentration: 4.0-8.0 ug/ml Magnification: 400X |
|
Image 2 | Human Jurkat
| WB Suggested Anti-ELK1 Antibody Titration: 2.5ug/ml ELISA Titer: 1:312500 Positive Control: Jurkat cell lysateELK1 is strongly supported by BioGPS gene expression data to be expressed in Human Jurkat cells |
|