Product Number |
ARP38544_P050 |
Product Page |
www.avivasysbio.com/pitx3-antibody-n-terminal-region-arp38544-p050.html |
Name |
PITX3 Antibody - N-terminal region (ARP38544_P050) |
Protein Size (# AA) |
302 amino acids |
Molecular Weight |
32 kDa |
NCBI Gene Id |
5309 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
0.5 mg/ml |
Gene Full Name |
Paired-like homeodomain 3 |
Alias Symbols |
ASMD, ASOD, PTX3, ASGD1, CTPP4, CTRCT11 |
Peptide Sequence |
Synthetic peptide located within the following region: ARSPALSLSDAGTPHPQLPEHGCKGQEHSDSEKASASLPGGSPEDGSLKK |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reference |
Bidinost,C., et al., (2006) Invest. Ophthalmol. Vis. Sci. 47 (4), 1274-1280 |
Description of Target |
PITX3 is a member of the RIEG/PITX homeobox family, which is in the bicoid class of homeodomain proteins. Members of this family act as transcription factors. Mutations of PITX3 have been associated with anterior segment mesenchymal dysgenesis (ASMD) and congenital cataracts. PITX3 is involved in lens formation during eye development.This gene encodes a member of the RIEG/PITX homeobox family, which is in the bicoid class of homeodomain proteins. Members of this family act as transcription factors. Mutations of this gene have been associated with anterior segment mesenchymal dysgenesis (ASMD) and congenital cataracts. This protein is involved in lens formation during eye development. |
Protein Interactions |
PARK7; MTA1; SFPQ; NONO; |
Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Enhanced Validation |
Relative Expression (Western Blot) |
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Datasheets/Manuals |
Printable datasheet for anti-PITX3 (ARP38544_P050) antibody |
Blocking Peptide |
For anti-PITX3 (ARP38544_P050) antibody is Catalog # AAP38544 (Previous Catalog # AAPP20735) |
Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human PITX3 |
Uniprot ID |
O75364 |
Protein Name |
Pituitary homeobox 3 |
Protein Accession # |
NP_005020 |
Purification |
Affinity Purified |
Nucleotide Accession # |
NM_005029 |
Tested Species Reactivity |
Human |
Gene Symbol |
PITX3 |
Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Sheep |
Application |
WB |
Predicted Homology Based on Immunogen Sequence |
Cow: 93%; Dog: 86%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Sheep: 93% |
Image 1 | Western Blot
| 25 ug of the indicated Human whole cell extracts was loaded onto a 12% SDS-PAGE gel. 1 ug/mL of the antibody was used in this experiment. |
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