PITX3 Antibody - N-terminal region (ARP38544_P050)

Data Sheet
 
Product Number ARP38544_P050
Product Page www.avivasysbio.com/pitx3-antibody-n-terminal-region-arp38544-p050.html
Name PITX3 Antibody - N-terminal region (ARP38544_P050)
Protein Size (# AA) 302 amino acids
Molecular Weight 32 kDa
NCBI Gene Id 5309
Host Rabbit
Clonality Polyclonal
Concentration 0.5 mg/ml
Gene Full Name Paired-like homeodomain 3
Alias Symbols ASMD, ASOD, PTX3, ASGD1, CTPP4, CTRCT11
Peptide Sequence Synthetic peptide located within the following region: ARSPALSLSDAGTPHPQLPEHGCKGQEHSDSEKASASLPGGSPEDGSLKK
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reference Bidinost,C., et al., (2006) Invest. Ophthalmol. Vis. Sci. 47 (4), 1274-1280
Description of Target PITX3 is a member of the RIEG/PITX homeobox family, which is in the bicoid class of homeodomain proteins. Members of this family act as transcription factors. Mutations of PITX3 have been associated with anterior segment mesenchymal dysgenesis (ASMD) and congenital cataracts. PITX3 is involved in lens formation during eye development.This gene encodes a member of the RIEG/PITX homeobox family, which is in the bicoid class of homeodomain proteins. Members of this family act as transcription factors. Mutations of this gene have been associated with anterior segment mesenchymal dysgenesis (ASMD) and congenital cataracts. This protein is involved in lens formation during eye development.
Protein Interactions PARK7; MTA1; SFPQ; NONO;
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Enhanced Validation
Relative Expression (Western Blot) Avivasheild
Datasheets/Manuals Printable datasheet for anti-PITX3 (ARP38544_P050) antibody
Blocking Peptide For anti-PITX3 (ARP38544_P050) antibody is Catalog # AAP38544 (Previous Catalog # AAPP20735)
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human PITX3
Uniprot ID O75364
Protein Name Pituitary homeobox 3
Protein Accession # NP_005020
Purification Affinity Purified
Nucleotide Accession # NM_005029
Tested Species Reactivity Human
Gene Symbol PITX3
Predicted Species Reactivity Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Sheep
Application WB
Predicted Homology Based on Immunogen Sequence Cow: 93%; Dog: 86%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Sheep: 93%
Image 1
Western Blot
25 ug of the indicated Human whole cell extracts was loaded onto a 12% SDS-PAGE gel. 1 ug/mL of the antibody was used in this experiment.
 

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