Product Number |
ARP38384_P050 |
Product Page |
www.avivasysbio.com/eed-antibody-n-terminal-region-arp38384-p050.html |
Name |
EED Antibody - N-terminal region (ARP38384_P050) |
Protein Size (# AA) |
400 amino acids |
Molecular Weight |
45kDa |
NCBI Gene Id |
8726 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
0.5 mg/ml |
Gene Full Name |
Embryonic ectoderm development |
Alias Symbols |
HEED, COGIS, WAIT1 |
Peptide Sequence |
Synthetic peptide located within the following region: QKLSSDENSNPDLSGDENDDAVSIESGTNTERPDTPTNTPNAPGRKSWGK |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Description of Target |
EED is a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein interacts with enhancer of zeste 2, the cytoplasmic tail of integrin beta7, immunodeficiency virus type 1 (HIV-1) MA protein, and histone deacetylase proteins. This protein mediates repression of gene activity through histone deacetylation, and may act as a specific regulator of integrin function. |
Protein Interactions |
PINK1; BRCA1; ADAM17; EZH2; IMP3; PSPC1; NAT10; PBRM1; RIF1; RBM28; HEATR1; MAGOHB; ARGLU1; MRPL20; NRDE2; CASZ1; BCOR; EXOSC4; LUC7L3; SF3B6; NOP58; SRRT; RAB14; C9orf114; CRNKL1; DDX47; HP1BP3; MYEF2; TRA2A; CPSF1; IGHV3-23; UTP20; PRPF19; ZNF638; RBMX; |
Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Datasheets/Manuals |
Printable datasheet for anti-EED (ARP38384_P050) antibody |
Blocking Peptide |
For anti-EED (ARP38384_P050) antibody is Catalog # AAP38384 (Previous Catalog # AAPP23152) |
Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human EED |
Uniprot ID |
O75530-3 |
Protein Name |
Polycomb protein EED |
Protein Accession # |
NP_694536 |
Purification |
Affinity Purified |
Nucleotide Accession # |
NM_152991 |
Tested Species Reactivity |
Human, Mouse |
Gene Symbol |
EED |
Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish |
Application |
WB |
Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 86% |
Image 1 | HepG2
| Host: Rabbit Target Name: EED Sample Type: HepG2 Lane A: Primary Antibody Lane B: Primary Antibody + Blocking Peptide Primary Antibody Concentration: 4.0ug/mL Peptide Concentration: 2.0ug/mL Lysate Quantity: 25ug/lane Gel Concentration: 12% |
|
Image 2 | Human HepG3
| Host: Rabbit Target Name: EED Sample Type: HepG2 Whole Cell lysates Antibody Dilution: 1.0ug/ml |
|
Image 3 | Mouse Kidney
| Host: Mouse Target Name: EED Sample Tissue: Mouse Kidney Antibody Dilution: 1ug/ml |
|