Product Number |
ARP38356_T100 |
Product Page |
www.avivasysbio.com/hmga2-antibody-n-terminal-region-arp38356-t100.html |
Name |
HMGA2 Antibody - N-terminal region (ARP38356_T100) |
Protein Size (# AA) |
109 amino acids |
Molecular Weight |
12kDa |
NCBI Gene Id |
8091 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
1.0 mg/ml |
Gene Full Name |
High mobility group AT-hook 2 |
Alias Symbols |
BABL, LIPO, SRS5, HMGIC, HMGI-C, STQTL9 |
Peptide Sequence |
Synthetic peptide located within the following region: PSTSAQGQPAAPAPQKRGRGRPRKQQQEPTGEPSPKRPRGRPKGSKNKSP |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reference |
Kubo,T., (2006) Biochem. Biophys. Res. Commun. 340 (2), 476-481 |
Description of Target |
HMGA2 belongs to the non-histone chromosomal high mobility group (HMG) protein family. HMG proteins function as architectural factors and are essential components of the enhancesome. This protein contains structural DNA-binding domains and may act as a transcriptional regulating factor. It may be play a role in adipogenesis, mesenchymal differentiation and diet-induced obesity.This gene encodes a protein that belongs to the non-histone chromosomal high mobility group (HMG) protein family. HMG proteins function as architectural factors and are essential components of the enhancesome. This protein contains structural DNA-binding domains and may act as a transcriptional regulating factor. Identification of the deletion, amplification, and rearrangement of this gene that are associated with myxoid liposarcoma suggests a role in adipogenesis and mesenchymal differentiation. A gene knock out study of the mouse counterpart demonstrated that this gene is involved in diet-induced obesity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. |
Protein Interactions |
PSIP1; SYNCRIP; PTBP1; PCBP2; PA2G4; NPM1; XRCC6; APEX1; HDGF; UBC; PRKCA; SMAD9; SMAD5; SMAD1; PRMT6; RB1; PIAS3; SMAD3; RELA; NFKB1; CDK1; CSNK2A2; CSNK2A1; |
Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Datasheets/Manuals |
Printable datasheet for anti-HMGA2 (ARP38356_T100) antibody |
Blocking Peptide |
For anti-HMGA2 (ARP38356_T100) antibody is Catalog # AAP38356 (Previous Catalog # AAPP20543) |
Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human HMGA2 |
Uniprot ID |
P52926 |
Protein Name |
High mobility group protein HMGI-C |
Sample Type Confirmation |
HMGA2 is supported by BioGPS gene expression data to be expressed in HEK293T |
Protein Accession # |
NP_003474 |
Purification |
Protein A purified |
Nucleotide Accession # |
NM_003483 |
Tested Species Reactivity |
Human |
Gene Symbol |
HMGA2 |
Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit, Yeast, Zebrafish |
Application |
WB |
Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Goat: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 92%; Zebrafish: 100% |
Image 1 | Human 293T
| Lanes: Lane 1: 5 ug 293T cell lysate Lane 2: 10 ug 293T cell lysate Lane 3: 20 ug 293T cell lysate Primary Antibody Dilution: 1:1000 Secondary Antibody: Anti-rabbit HRP Secondary Antibody Dilution: 1:10000 Gene Name: HMGA2 Submitted by: Anonymous HMGA2 is supported by BioGPS gene expression data to be expressed in HEK293T |
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