ZNF76 Antibody - N-terminal region (ARP38325_T100)

Data Sheet
 
Product Number ARP38325_T100
Product Page www.avivasysbio.com/znf76-antibody-n-terminal-region-arp38325-t100.html
Name ZNF76 Antibody - N-terminal region (ARP38325_T100)
Protein Size (# AA) 570 amino acids
Molecular Weight 62kDa
NCBI Gene Id 7629
Host Rabbit
Clonality Polyclonal
Concentration 1.0 mg/ml
Gene Full Name Zinc finger protein 76
Alias Symbols ZNF523, Zfp523, D6S229E
Peptide Sequence Synthetic peptide located within the following region: LSDGTTAYVQQAVKGEKLLEGQVIQLEDGTTAYIHQVTVQKEALSFEDGQ
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reference Zheng,G. (2006) Biochem. Biophys. Res. Commun. 339 (4), 1069-1075
Description of Target ZNF76 belongs to the krueppel C2H2-type zinc-finger protein family. ZNF76 is a general transcription repressor targeting TATA-binding protein (TBP), through a process regulated by sumoylation. ZNF76 interacts with TBP through both its N and C termini, and both regions are required for ZNF76 to exert its inhibitory function on p53-mediated transactivation. As a TBP-interacting transcriptional modulator, ZNF76 is also regulated by alternative splicing.
Protein Interactions SMAD1; UBC; TBP; HDAC1; EP300; CAND1; ELAVL1; Pias1;
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for anti-ZNF76 (ARP38325_T100) antibody
Blocking Peptide For anti-ZNF76 (ARP38325_T100) antibody is Catalog # AAP38325 (Previous Catalog # AAPP20512)
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human ZNF76
Uniprot ID P36508
Protein Name Zinc finger protein 76
Protein Accession # NP_003418
Purification Protein A purified
Nucleotide Accession # NM_003427
Tested Species Reactivity Human
Gene Symbol ZNF76
Predicted Species Reactivity Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish
Application WB
Predicted Homology Based on Immunogen Sequence Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 86%
Image 1
Human HepG2
WB Suggested Anti-ZNF76 Antibody Titration: 1.25ug/ml
ELISA Titer: 1:312500
Positive Control: HepG2 cell lysate
 

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