Product Number |
ARP38218_T100 |
Product Page |
www.avivasysbio.com/smarca3-antibody-c-terminal-region-arp38218-t100.html |
Name |
SMARCA3 Antibody - C-terminal region (ARP38218_T100) |
Protein Size (# AA) |
1009 amino acids |
Molecular Weight |
114kDa |
NCBI Gene Id |
6596 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
1.0 mg/ml |
Gene Full Name |
Helicase-like transcription factor |
Alias Symbols |
ZBU1, HLTF1, RNF80, HIP116, SNF2L3, HIP116A, SMARCA3 |
Peptide Sequence |
Synthetic peptide located within the following region: FIVKDSVEENMLKIQNKKRELAAGAFGTKKPNADEMKQAKINEIRTLIDL |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reference |
Beausoleil,S.A., (2004) Proc. Natl. Acad. Sci. U.S.A. 101 (33), 12130-12135 |
Description of Target |
SMARCA3 (HLTF) is a member of the SWI/SNF family. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. SMARCA3 contains a RING finger DNA binding motif. Western blots using two different antibodies against two unique regions of this protein target confirm the same apparent molecular weight in our tests.The protein encoded by this gene is a member of the SWI/SNF family of proteins. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein contains a RING finger DNA binding motif. Two transcript variants encoding the same protein have been found for this gene. However, use of an alternative translation start site produces an isoform which is truncated at the N-terminus as compared to the full-length protein. |
Protein Interactions |
CHFR; UBC; RAD18; SUMO2; RPA3; RPA2; RPA1; WBP4; BRCA1; DTL; SULT1C2; HSPA8; CDK9; NOTCH1; SP3; SP1; SPRTN; Cebpb; ELAVL1; Shprh; RNF146; tat; EWSR1; UBE2Z; RPAP1; USP7; EEF1G; UBE2V2; UBE2N; PCNA; |
Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Datasheets/Manuals |
Printable datasheet for anti-HLTF (ARP38218_T100) antibody |
Blocking Peptide |
For anti-HLTF (ARP38218_T100) antibody is Catalog # AAP38218 (Previous Catalog # AAPP20394) |
Immunogen |
The immunogen is a synthetic peptide directed towards the C terminal region of human SMARCA3 |
Uniprot ID |
Q14527 |
Protein Name |
Helicase-like transcription factor |
Protein Accession # |
NP_620636 |
Purification |
Protein A purified |
Nucleotide Accession # |
NM_139048 |
Tested Species Reactivity |
Human |
Gene Symbol |
HLTF |
Predicted Species Reactivity |
Human, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit |
Application |
WB |
Predicted Homology Based on Immunogen Sequence |
Cow: 86%; Dog: 86%; Guinea Pig: 86%; Horse: 79%; Human: 100%; Rabbit: 86%; Rat: 86% |
Image 1 | Transfected 293T
| WB Suggested Anti-SMARCA3 Antibody Titration: 5.0ug/ml ELISA Titer: 1:62500 Positive Control: Transfected 293T |
|