SATB1 Antibody - C-terminal region (ARP38208_T100)

• Product Number: ARP38208_T100
• Name: SATB1 Antibody - C-terminal region (ARP38208_T100)
• Protein Size (# AA): 763 amino acids
• Molecular Weight: 86 kDa
• NCBI Gene Id: 6304
• Host: Rabbit
• Clonality: Polyclonal
• Concentration: 1.0 mg/ml
• Gene Full Name: SATB homeobox 1
• Alias Symbols: DEFDA, KTZSL
• Peptide Sequence: Synthetic peptide located within the following region: VDVAEYKEEELLKDLEESVQDKNTNTLFSVKLEEELSVEGNTDINTDLKD
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Reference: Pavan., et al., (2006) Mol. Cell 22 (2), 231-243
• Description of Target: SATB1 binds to DNA at special AT-rich sequences at nuclear matrix- or scaffold-associated regions. SATB1 was thought to recognize the sugar-phosphate structure of double-stranded DNA
• Protein Interactions: SUMO1P1; UBE2I; SUMO1; SUMO3; PML; CASP6; PIAS4; PIAS3; TOPORS; PIAS1; CBX4; SIRT1; UBC; CTNNB1; UBR5; tat; TAL1; HDAC1; DYT10; KAT2B; CTBP1; POLR2J; BAZ1A; CHD3; MTA2; SMARCA5; EP300; SATB1; GATA3; CUX1; SIN3A; HDAC2; CHD4;
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Enhanced Validation: Relative Expression (Western Blot)
  
• Blocking Peptide: For anti-SATB1 (ARP38208_T100) antibody is Catalog # AAP38208 (Previous Catalog # AAPP20384)
• Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human SATB1
• Uniprot ID: Q01826
• Protein Name: DNA-binding protein SATB1
• Sample Type Confirmation:

  SATB1 is supported by BioGPS gene expression data to be expressed in Jurkat

• Protein Accession #: NP_002962
• Purification: Protein A purified
• Nucleotide Accession #: NM_002971
• Tested Species Reactivity: Human
• Gene Symbol: SATB1
• Predicted Species Reactivity: Human, Mouse, Rat, Guinea Pig, Horse, Rabbit
• Application: WB
• Predicted Homology Based on Immunogen Sequence: Guinea Pig: 86%; Horse: 93%; Human: 100%; Mouse: 79%; Rabbit: 86%; Rat: 93%
• Image 1:
  
  25 ug of the indicated Human whole cell extracts was loaded onto a 12% SDS-PAGE gel. 3 ug/mL of the antibody was used in this experiment. The peptide is present in 3 isoforms including 89 kDa, 86 kDa, and 78 kDa. The protein may be modified by phosphorylation and/or sumoylation.