PBX2 Antibody - C-terminal region (ARP38173_T100)

Data Sheet
 
Product Number ARP38173_T100
Product Page www.avivasysbio.com/pbx2-antibody-c-terminal-region-arp38173-t100.html
Name PBX2 Antibody - C-terminal region (ARP38173_T100)
Protein Size (# AA) 430 amino acids
Molecular Weight 46kDa
NCBI Gene Id 5089
Host Rabbit
Clonality Polyclonal
Concentration 1.0 mg/ml
Gene Full Name Pre-B-cell leukemia homeobox 2
Alias Symbols G17, HOX12, PBX2MHC
Peptide Sequence Synthetic peptide located within the following region: PGGYGDNLGGGQMYSPREMRANGSWQEAVTPSSVTSPTEGPGSVHSDTSN
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reference Lehner,B., et al., (2004) Genomics 83 (1), 153-167
Description of Target PBX2 is a ubiquitously expressed member of the TALE/PBX homeobox family. PBX2 gene was identified by its similarity to a homeobox gene which is involved in t(1;19) translocation in acute pre-B-cell leukemias. PBX2 is a transcriptional activator which binds to the TLX1 promoter. This gene encodes a ubiquitously expressed member of the TALE/PBX homeobox family. It was identified by its similarity to a homeobox gene which is involved in t(1;19) translocation in acute pre-B-cell leukemias. This protein is a transcriptional activator which binds to the TLX1 promoter. The gene is located within the major histocompatibility complex (MHC) on chromosome 6.
Protein Interactions CARD9; HOXA1; SOX2; ELAVL1; COPS6; ZDHHC7; SKIV2L2; SMYD3; MCRS1; CCDC88B; RPS6KC1; PBX2; PBX1; CENPBD1; DCTN3; NUP62; BAIAP2; IKBKAP; UBE2E1; PKNOX1; BLOC1S1; RPL4; HOXB8; HOXA9;
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for anti-PBX2 (ARP38173_T100) antibody
Blocking Peptide For anti-PBX2 (ARP38173_T100) antibody is Catalog # AAP38173 (Previous Catalog # AAPP20349)
Immunogen The immunogen is a synthetic peptide directed towards the C terminal region of human PBX2
Uniprot ID P40425
Protein Name Pre-B-cell leukemia transcription factor 2
Sample Type Confirmation

PBX2 is supported by BioGPS gene expression data to be expressed in Jurkat

Protein Accession # NP_002577
Purification Protein A purified
Nucleotide Accession # NM_002586
Tested Species Reactivity Human
Gene Symbol PBX2
Predicted Species Reactivity Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish
Application WB
Predicted Homology Based on Immunogen Sequence Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%
Image 1
Human Jurkat
WB Suggested Anti-PBX2 Antibody Titration: 1.25ug/ml
ELISA Titer: 1:62500
Positive Control: Jurkat cell lysatePBX2 is supported by BioGPS gene expression data to be expressed in Jurkat
 

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