| Product Number |
ARP38153_T100 |
| Product Page |
www.avivasysbio.com/msx2-antibody-n-terminal-region-arp38153-t100.html |
| Name |
MSX2 Antibody - N-terminal region (ARP38153_T100) |
| Protein Size (# AA) |
267 amino acids |
| Molecular Weight |
29kDa |
| NCBI Gene Id |
4488 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
1.0 mg/ml |
| Gene Full Name |
Msh homeobox 2 |
| Alias Symbols |
FPP, MSH, PFM, CRS2, HOX8, PFM1 |
| Peptide Sequence |
Synthetic peptide located within the following region: MASPSKGNDLFSPDEEGPAVVAGPGPGPGGAEGAAEERRVKVSSLPFSVE |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Le (2006) Calcif. Tissue Int. 78 (2), 98-102 |
| Description of Target |
MSX2 is a member of the muscle segment homeobox gene family. The protein is a transcriptional repressor whose normal activity may establish a balance between survival and apoptosis of neural crest-derived cells required for proper craniofacial morphogenesis. The protein may also have a role in promoting cell growth under certain conditions and may be an important target for the RAS signaling pathways. Mutations in this gene are associated with parietal foramina 1 and craniosynostosis type 2.This gene encodes a member of the muscle segment homeobox gene family. The encoded protein is a transcriptional repressor whose normal activity may establish a balance between survival and apoptosis of neural crest-derived cells required for proper craniofacial morphogenesis. The encoded protein may also have a role in promoting cell growth under certain conditions and may be an important target for the RAS signaling pathways. Mutations in this gene are associated with parietal foramina 1 and craniosynostosis type 2. |
| Protein Interactions |
ATXN1; PIAS2; UBC; XRCC5; XRCC6; ZDHHC2; TLE2; TLE1; PPARG; POU2AF1; NR3C1; POLR3D; SPEN; ZBTB17; RUNX2; DLX5; MAGED1; GTF2F2; GTF2F1; MSX1; DLX2; MSX2; CEBPA; PITX2; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Enhanced Validation |
| Relative Expression (Western Blot) |
 |
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| Datasheets/Manuals |
Printable datasheet for anti-MSX2 (ARP38153_T100) antibody |
| Blocking Peptide |
For anti-MSX2 (ARP38153_T100) antibody is Catalog # AAP38153 (Previous Catalog # AAPS04905) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human MSX2 |
| Uniprot ID |
P35548 |
| Protein Name |
Homeobox protein MSX-2 |
| Protein Accession # |
NP_002440 |
| Purification |
Protein A purified |
| Nucleotide Accession # |
NM_002449 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
MSX2 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Goat, Horse, Rabbit |
| Application |
IHC, WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Goat: 93%; Horse: 100%; Human: 100%; Mouse: 93%; Rabbit: 93%; Rat: 93% |
| Image 1 | Human kidney
 | Human kidney |
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| Image 2 |
 | 25 ug of the indicated Human whole cell extracts was loaded onto a 12% SDS-PAGE gel. 3 ug/mL of the antibody was used in this experiment.
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