| Product Number |
ARP38131_T100 |
| Product Page |
www.avivasysbio.com/irf5-antibody-n-terminal-region-arp38131-t100.html |
| Name |
IRF5 Antibody - N-terminal region (ARP38131_T100) |
| Protein Size (# AA) |
498 amino acids |
| Molecular Weight |
56kDa |
| NCBI Gene Id |
3663 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
1.0 mg/ml |
| Gene Full Name |
Interferon regulatory factor 5 |
| Alias Symbols |
SLEB10 |
| Peptide Sequence |
Synthetic peptide located within the following region: PTPPRRVRLKPWLVAQVNSCQYPGLQWVNGEKKLFCIPWRHATRHGPSQD |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Mancl,M.E., et al., (2005) J. Biol. Chem. 280 (22), 21078-21090 |
| Description of Target |
IRF5 is a member of the interferon regulatory factor (IRF) family, a group of transcription factors with diverse roles, including virus-mediated activation of interferon, and modulation of cell growth, differentiation, apoptosis, and immune system activity. Members of the IRF family are characterized by a conserved N-terminal DNA-binding domain containing tryptophan (W) repeats. Alternative splice variants encoding different isoforms exist. |
| Protein Interactions |
SGTA; IRF5; COPS7B; COPS4; COPS5; COPS6; COPS8; COPS2; COPS3; UBC; GPS1; TRAF6; MYD88; RGS3; PPM1G; IRF6; HIVEP1; GRB2; CHUK; ALPI; MAVS; GTPBP2; CEP152; GTPBP1; SIN3A; NCOR2; NCOR1; KAT2B; HDAC1; EP300; CREBBP; TRIM15; IKBKE; TBK1; IRF3; XPO1; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-IRF5 (ARP38131_T100) antibody |
| Blocking Peptide |
For anti-IRF5 (ARP38131_T100) antibody is Catalog # AAP38131 (Previous Catalog # AAPP10018) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human IRF5 |
| Uniprot ID |
Q13568 |
| Protein Name |
Interferon regulatory factor 5 |
| Protein Accession # |
NP_116032 |
| Purification |
Protein A purified |
| Nucleotide Accession # |
NM_032643 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
IRF5 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 93%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 77% |
| Image 1 | Human HepG2
 | WB Suggested Anti-IRF5 Antibody Titration: 2.5ug/ml
ELISA Titer: 1:312500
Positive Control: HepG2 cell lysate |
|
