HMGA1 Antibody - N-terminal region (ARP38111_P050)

• Product Number: ARP38111_P050
• Name: HMGA1 Antibody - N-terminal region (ARP38111_P050)
• Protein Size (# AA): 96 amino acids
• Molecular Weight: 11kDa
• NCBI Gene Id: 3159
• Host: Rabbit
• Clonality: Polyclonal
• Concentration: 0.5 mg/ml
• Gene Full Name: High mobility group AT-hook 1
• Alias Symbols: HMG-R, HMGIY, HMGA1A
• Peptide Sequence: Synthetic peptide located within the following region: MSESSSKSSQPLASKQEKDGTEKRGRGRPRKQPPKEPSEVPTPKRPRGRP
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Description of Target: This gene encodes a non-histone protein involved in many cellular processes, including regulation of inducible gene transcription, integration of retroviruses into chromosomes, and the metastatic progression of cancer cells. The encoded protein preferentially binds to the minor groove of A+T-rich regions in double-stranded DNA. It has little secondary structure in solution but assumes distinct conformations when bound to substrates such as DNA or other proteins. The encoded protein is frequently acetylated and is found in the nucleus. At least seven transcript variants encoding two different isoforms have been found for this gene.
• Protein Interactions: NCOR2; UBE2I; PPARG; UBC; UPF2; HTT; OLA1; DNAJC8; PSIP1; METAP2; SYNCRIP; CWC27; HNRNPDL; EIF2S2; PCBP2; PCBP1; PA2G4; NPM1; NCL; HSPA1A; HNRNPL; HNRNPD; HNRNPAB; HNRNPA1; HMGB3; HMGB2; HMGB1; GTF2F2; XRCC6; CSNK2A1; RCC1; CDK1; APEX1; ANXA2; ANXA1; SSB;
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Blocking Peptide: For anti-HMGA1 (ARP38111_P050) antibody is Catalog # AAP38111 (Previous Catalog # AAPS04801)
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human HMGA1
• Uniprot ID: Q5T6U8
• Protein Name: High mobility group AT-hook 1 EMBL CAI14992.1
• Sample Type Confirmation:

  HMGA1 is strongly supported by BioGPS gene expression data to be expressed in HT1080

• Protein Accession #: NP_002122
• Purification: Affinity Purified
• Nucleotide Accession #: NM_002131
• Tested Species Reactivity: Human
• Gene Symbol: HMGA1
• Predicted Species Reactivity: Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit, Yeast, Zebrafish
• Application: WB
• Predicted Homology Based on Immunogen Sequence: Cow: 93%; Dog: 100%; Goat: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 100%; Zebrafish: 86%
• Image 1: Human HT1080
  
  WB Suggested Anti-HMGA1 Antibody Titration: 0.2-1 ug/ml
  ELISA Titer: 1:312500
  Positive Control: HT1080 cell lysateHMGA1 is strongly supported by BioGPS gene expression data to be expressed in Human HT1080 cells