| Product Number |
ARP38096_T100 |
| Product Page |
www.avivasysbio.com/fli1-antibody-n-terminal-region-arp38096-t100.html |
| Name |
FLI1 Antibody - N-terminal region (ARP38096_T100) |
| Protein Size (# AA) |
452 amino acids |
| Molecular Weight |
51kDa |
| NCBI Gene Id |
2313 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
1.0 mg/ml |
| Gene Full Name |
Friend leukemia virus integration 1 |
| Alias Symbols |
EWSR2, SIC-1, BDPLT21 |
| Peptide Sequence |
Synthetic peptide located within the following region: MDGTIKEALSVVSDDQSLFDSAYGAAAHLPKADMTASGSPDYGQPHKINP |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
van den Akker,E., et al., (2005) J. Biol. Chem. 280 (45), 38035-38046 |
| Description of Target |
Friend leukemia integration 1 (Fli-1) is a member of the ETS family of transcriptional regulatory proteins that contain a highly conserved and structurally unique DNA binding ETS domain. |
| Protein Interactions |
SOX30; SIAH1; CTBP2; UBC; SMAD9; GATA1; FMNL1; SUMO1; UBE2I; PIAS2; PIAS1; SMAD3; ETV6; KLF1; TDP2; SRF; ERG; EWSR1; ELK1; BRCA1; TGFBR2; STYXL1; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-FLI1 (ARP38096_T100) antibody |
| Blocking Peptide |
For anti-FLI1 (ARP38096_T100) antibody is Catalog # AAP38096 (Previous Catalog # AAPP20270) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human FLI1 |
| Uniprot ID |
Q01543 |
| Protein Name |
Friend leukemia integration 1 transcription factor |
| Publications |
Bujor, A. M. et al. Ciprofloxacin has antifibrotic effects in scleroderma fibroblasts via downregulation of Dnmt1 and upregulation of Fli1. Int. J. Mol. Med. 30, 1473-80 (2012). 23041765 |
| Sample Type Confirmation |
FLI1 is strongly supported by BioGPS gene expression data to be expressed in Jurkat |
| Protein Accession # |
NP_002008 |
| Purification |
Protein A purified |
| Nucleotide Accession # |
NM_002017 |
| Tested Species Reactivity |
Human, Pig |
| Gene Symbol |
FLI1 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 79% |
| Image 1 | Porcine endothelial
 | FLI1 antibody - N-terminal region (ARP38096_T100) validated by WB using porcine endothelial cell at 1:1000. |
|
| Image 2 | Human Jurkat
 | WB Suggested Anti-FLI1 Antibody Titration: 1.25ug/ml
ELISA Titer: 1:312500
Positive Control: Jurkat cell lysateFLI1 is strongly supported by BioGPS gene expression data to be expressed in Human Jurkat cells |
|
