Product Number |
ARP38085_T100 |
Product Page |
www.avivasysbio.com/dr1-antibody-n-terminal-region-arp38085-t100.html |
Name |
DR1 Antibody - N-terminal region (ARP38085_T100) |
Protein Size (# AA) |
176 amino acids |
Molecular Weight |
19kDa |
NCBI Gene Id |
1810 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
1.0 mg/ml |
Gene Full Name |
Down-regulator of transcription 1, TBP-binding (negative cofactor 2) |
Alias Symbols |
NC2, NC2B, NCB2, NC2-BETA |
Peptide Sequence |
Synthetic peptide located within the following region: MASSSGNDDDLTIPRAAINKMIKETLPNVRVANDARELVVNCCTEFIHLI |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reference |
Gilfillan,S., et al., (2005) J. Biol. Chem. 280 (7), 6222-6230 |
Description of Target |
DR1 is a TBP- (TATA box-binding protein) associated phosphoprotein that represses both basal and activated levels of transcription. DR1 is phosphorylated in vivo and this phosphorylation affects its interaction with TBP. DR1 contains a histone fold motif |
Protein Interactions |
POLE3; TBP; UBC; BTF3L4; LRSAM1; GOPC; NPLOC4; IPO11; DBNL; ARIH1; TTLL12; ARPC1B; UBE3A; METTL1; HSF1; XPO1; YEATS2; DRAP1; CREB1; CCDC101; TADA2B; SUPT20H; MBIP; WDR5; TADA3; KAT2B; MAP3K7; TADA2A; KAT2A; DR1; ELAVL1; NFYC; NFIL3; TTF2; IRF1; |
Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Datasheets/Manuals |
Printable datasheet for anti-DR1 (ARP38085_T100) antibody |
Blocking Peptide |
For anti-DR1 (ARP38085_T100) antibody is Catalog # AAP38085 (Previous Catalog # AAPP20259) |
Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human DR1 |
Uniprot ID |
Q01658 |
Protein Name |
Protein Dr1 |
Publications |
Deng, W., Malecová, B., Oelgeschläger, T. & Roberts, S. G. E. TFIIB recognition elements control the TFIIA-NC2 axis in transcriptional regulation. Mol. Cell. Biol. 29, 1389-400 (2009). 19114554 |
Protein Accession # |
NP_001929 |
Purification |
Protein A purified |
Nucleotide Accession # |
NM_001938 |
Tested Species Reactivity |
Human |
Gene Symbol |
DR1 |
Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish |
Application |
WB |
Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100% |
Image 1 | Transfected 293T
| WB Suggested Anti-DR1 Antibody Titration: 1.25ug/ml ELISA Titer: 1:62500 Positive Control: Transfected 293T |
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