DR1 Antibody - N-terminal region (ARP38085_T100)

Data Sheet
 
Product Number ARP38085_T100
Product Page www.avivasysbio.com/dr1-antibody-n-terminal-region-arp38085-t100.html
Name DR1 Antibody - N-terminal region (ARP38085_T100)
Protein Size (# AA) 176 amino acids
Molecular Weight 19kDa
NCBI Gene Id 1810
Host Rabbit
Clonality Polyclonal
Concentration 1.0 mg/ml
Gene Full Name Down-regulator of transcription 1, TBP-binding (negative cofactor 2)
Alias Symbols NC2, NC2B, NCB2, NC2-BETA
Peptide Sequence Synthetic peptide located within the following region: MASSSGNDDDLTIPRAAINKMIKETLPNVRVANDARELVVNCCTEFIHLI
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reference Gilfillan,S., et al., (2005) J. Biol. Chem. 280 (7), 6222-6230
Description of Target DR1 is a TBP- (TATA box-binding protein) associated phosphoprotein that represses both basal and activated levels of transcription. DR1 is phosphorylated in vivo and this phosphorylation affects its interaction with TBP. DR1 contains a histone fold motif
Protein Interactions POLE3; TBP; UBC; BTF3L4; LRSAM1; GOPC; NPLOC4; IPO11; DBNL; ARIH1; TTLL12; ARPC1B; UBE3A; METTL1; HSF1; XPO1; YEATS2; DRAP1; CREB1; CCDC101; TADA2B; SUPT20H; MBIP; WDR5; TADA3; KAT2B; MAP3K7; TADA2A; KAT2A; DR1; ELAVL1; NFYC; NFIL3; TTF2; IRF1;
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for anti-DR1 (ARP38085_T100) antibody
Blocking Peptide For anti-DR1 (ARP38085_T100) antibody is Catalog # AAP38085 (Previous Catalog # AAPP20259)
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human DR1
Uniprot ID Q01658
Protein Name Protein Dr1
Publications

Deng, W., Malecová, B., Oelgeschläger, T. & Roberts, S. G. E. TFIIB recognition elements control the TFIIA-NC2 axis in transcriptional regulation. Mol. Cell. Biol. 29, 1389-400 (2009). 19114554

Protein Accession # NP_001929
Purification Protein A purified
Nucleotide Accession # NM_001938
Tested Species Reactivity Human
Gene Symbol DR1
Predicted Species Reactivity Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish
Application WB
Predicted Homology Based on Immunogen Sequence Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%
Image 1
Transfected 293T
WB Suggested Anti-DR1 Antibody Titration: 1.25ug/ml
ELISA Titer: 1:62500
Positive Control: Transfected 293T
 

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