| Product Number |
ARP38073_P050 |
| Product Page |
www.avivasysbio.com/runx1-antibody-n-terminal-region-arp38073-p050.html |
| Name |
RUNX1 Antibody - N-terminal region (ARP38073_P050) |
| Protein Size (# AA) |
107 amino acids |
| Molecular Weight |
12kDa |
| NCBI Gene Id |
861 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
Runt-related transcription factor 1 |
| Alias Symbols |
AML1, CBFA2, EVI-1, AMLCR1, PEBP2aB, CBF2alpha, AML1-EVI-1, PEBP2alpha |
| Peptide Sequence |
Synthetic peptide located within the following region: KMPAAPRGPAQGEAAARTRSRDASTSRRFTPPSTALSPGKMSEALPLGAP |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Ghozi,M.C., et al., (1996) Proc. Natl. Acad. Sci. U.S.A. 93 (5), 1935-1940 |
| Description of Target |
Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. RUNX1 is the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with severaltypes of leukemia. |
| Protein Interactions |
YAP1; UBC; HDAC11; SOX2; SMAD3; CTBP1; RUNX1; FOXP3; NCOR2; MYC; NOTCH1; UXT; CTBP2; KAT6A; PML; CREBBP; CBFB; PRMT1; HLA-DMA; HDAC2; HDAC1; CBFA2T3; RUNX1T1; CBFA2T2; ELAVL1; DNMT1; SPEN; RBM14; KMT2A; COPRS; HDAC3; TAL1; CDK1; SMARCC1; SMARCB1; SMARCA4; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-RUNX1 (ARP38073_P050) antibody |
| Blocking Peptide |
For anti-RUNX1 (ARP38073_P050) antibody is Catalog # AAP38073 (Previous Catalog # AAPP20247) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human RUNX1 |
| Uniprot ID |
Q01196 |
| Protein Name |
Runt-related transcription factor 1 |
| Sample Type Confirmation |
RUNX1 is strongly supported by BioGPS gene expression data to be expressed in Jurkat |
| Protein Accession # |
AAC05247 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_001001890 |
| Tested Species Reactivity |
Human, Mouse |
| Gene Symbol |
RUNX1 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 86% |
| Image 1 | Human Jurkat
 | WB Suggested Anti-RUNX1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:12500
Positive Control: Jurkat cell lysateRUNX1 is strongly supported by BioGPS gene expression data to be expressed in Human Jurkat cells |
|
| Image 2 | Mouse Brain
 | Host: Mouse
Target Name: RUNX1
Sample Tissue: Mouse Brain
Antibody Dilution: 1ug/ml |
|
