| Product Number |
ARP38012_T100 |
| Product Page |
www.avivasysbio.com/bach1-antibody-c-terminal-region-arp38012-t100.html |
| Name |
BACH1 Antibody - C-terminal region (ARP38012_T100) |
| Protein Size (# AA) |
736 amino acids |
| Molecular Weight |
82kDa |
| NCBI Gene Id |
571 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
1.0 mg/ml |
| Gene Full Name |
BTB and CNC homology 1, basic leucine zipper transcription factor 1 |
| Alias Symbols |
BACH-1, BTBD24 |
| Peptide Sequence |
Synthetic peptide located within the following region: PPCARGNSEPGYARGQESQQMSTATSEQAGPAEQCRQSGGISDFCQQMTD |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Litman,R., et al., (2005) Cancer Cell 8 (3), 255-265 |
| Description of Target |
BACH1 is a transcription factor that belongs to the cap'n'collar type of basic region leucine zipper factor family (CNC-bZip). The encoded protein contains broad complex, tramtrack, bric-a-brac/poxvirus and zinc finger (BTB/POZ) domains, which is atypical of CNC-bZip family members. These BTB/POZ domains facilitate protein-protein interactions and formation of homo- and/or hetero-oligomers. When this encoded protein forms a heterodimer with MafK, it functions as a repressor of Maf recognition element (MARE) and transcription is repressed. Multiple alternatively spliced transcript variants have been identified for this gene. Some exons of this gene overlap with some exons from the C21orf41 gene, which is transcribed in an opposite orientation to this gene but does not seem to encode a protein. |
| Protein Interactions |
NFE2L2; BRCA1; SMAD3; FBXL17; NLK; UBC; MAFF; MAFB; MAFG; DDIT3; ATF2; CSNK1A1; ANAPC5; PALB2; TOPBP1; NBN; MRE11A; MLH1; BARD1; Bach1; HMMR; BRCA2; BRCC3; XPO1; NCOR1; MAFK; TP53; HDAC1; PATZ1; RBCK1; PARK2; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-BACH1 (ARP38012_T100) antibody |
| Blocking Peptide |
For anti-BACH1 (ARP38012_T100) antibody is Catalog # AAP38012 (Previous Catalog # AAPP20185) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the C terminal region of human BACH1 |
| Uniprot ID |
O14867 |
| Protein Name |
Transcription regulator protein BACH1 |
| Protein Accession # |
NP_001177 |
| Purification |
Protein A purified |
| Nucleotide Accession # |
NM_001186 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
BACH1 |
| Predicted Species Reactivity |
Human |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Human: 100% |
| Image 1 | Human Jurkat
 | WB Suggested Anti-BACH1 Antibody Titration: 1.25ug/ml
ELISA Titer: 1:1562500
Positive Control: Jurkat cell lysate |
|
|
