Product Number |
ARP37988_P050 |
Product Page |
www.avivasysbio.com/wt1-antibody-n-terminal-region-arp37988-p050.html |
Name |
WT1 Antibody - N-terminal region (ARP37988_P050) |
Protein Size (# AA) |
497 amino acids |
Molecular Weight |
54kDa |
NCBI Gene Id |
7490 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
0.5 mg/ml |
Gene Full Name |
Wilms tumor 1 |
Alias Symbols |
GUD, AWT1, WAGR, WT33, NPHS4, WIT-2 |
Peptide Sequence |
Synthetic peptide located within the following region: PASQHTLRSGPGCLQQPEQQGVRDPGGIWAKLGAAEASAERLQGRRSRGA |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Description of Target |
WT1 is a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the normal development of the urogenital system, and it is mutated in a small subset of patients with Wilm's tumors. Multiple transcript variants, resulting from alternative splicing at two coding exons, have been well characterized. There is also evidence for the use of non-AUG (CUG) translation initiation site upstream of, and in-frame with the first AUG, leading to additional isoforms. |
Protein Interactions |
KRTAP10-3; KRTAP10-8; KRT40; EGR1; MDM2; DVL3; CIAO1; TP53; HSPA4; TAOK1; NPM3; ZNF205; SUZ12; MEN1; EZH2; DNMT1; WTIP; WTAP; PAWR; UBE2I; TP63; FHL2; TP73; PRKACA; CREBBP; U2AF2; PAX2; AREG; |
Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Datasheets/Manuals |
Printable datasheet for anti-WT1 (ARP37988_P050) antibody |
Blocking Peptide |
For anti-WT1 (ARP37988_P050) antibody is Catalog # AAP37988 (Previous Catalog # AAPP20090) |
Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human WT1 |
Uniprot ID |
E9PMK7 |
Protein Accession # |
NP_000369 |
Purification |
Affinity Purified |
Nucleotide Accession # |
NM_000378 |
Tested Species Reactivity |
Human |
Gene Symbol |
WT1 |
Predicted Species Reactivity |
Human |
Application |
WB |
Predicted Homology Based on Immunogen Sequence |
Human: 100% |
Image 1 | Human HeLa
| WB Suggested Anti-WT1 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:312500 Positive Control: Hela cell lysate |
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