Product Number |
ARP37969_P050 |
Product Page |
www.avivasysbio.com/fbn1-antibody-n-terminal-region-arp37969-p050.html |
Name |
FBN1 Antibody - N-terminal region (ARP37969_P050) |
Protein Size (# AA) |
195 amino acids |
Molecular Weight |
21kDa |
NCBI Gene Id |
2200 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
0.5 mg/ml |
Gene Full Name |
Fibrillin 1 |
Alias Symbols |
FBN, SGS, WMS, MASS, MFLS, MFS1, OCTD, SSKS, WMS2, ACMICD, ECTOL1, GPHYSD2 |
Peptide Sequence |
Synthetic peptide located within the following region: MRRGRLLEIALGFTVLLASYTSHGADANLEAGNVKETRASRAKRRGGGGH |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reference |
Uyeda,T., et al., (2004) J. Hum. Genet. 49 (8), 404-407 |
Description of Target |
FBN1 is a member of the fibrillin family. FBN1 is a large, extracellular matrix glycoprotein that serve as a structural component of 10-12 nm calcium-binding microfibrils. These microfibrils provide force bearing structural support in elastic and nonelastic connective tissue throughout the body. Mutations in this gene are associated with Marfan syndrome, isolated ectopia lentis, autosomal dominant Weill-Marchesani syndrome, MASS syndrome, and Shprintzen-Goldberg craniosynostosis syndrome. |
Protein Interactions |
UBC; SPRY2; ATXN7; MYOC; MFAP5; MFAP2; LTBP1; HSPG2; FBLN2; ELN; DCN; FBN2; VCAN; CALR; |
Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Datasheets/Manuals |
Printable datasheet for anti-FBN1 (ARP37969_P050) antibody |
Blocking Peptide |
For anti-FBN1 (ARP37969_P050) antibody is Catalog # AAP37969 (Previous Catalog # AAPP20072) |
Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human FBN1 |
Uniprot ID |
Q75N89 |
Protein Name |
Fibrillin 1 EMBL BAD16737.1 |
Protein Accession # |
BAD16737 |
Purification |
Affinity Purified |
Nucleotide Accession # |
NM_000138 |
Tested Species Reactivity |
Human |
Gene Symbol |
FBN1 |
Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit |
Application |
WB |
Predicted Homology Based on Immunogen Sequence |
Cow: 93%; Dog: 100%; Guinea Pig: 86%; Horse: 100%; Human: 100%; Mouse: 79%; Pig: 93%; Rabbit: 100%; Rat: 79% |
Image 1 | Human Jurkat
| WB Suggested Anti-FBN1 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:1562500 Positive Control: Jurkat cell lysate |
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