Product Number |
ARP37738_T100 |
Product Page |
www.avivasysbio.com/mta1-antibody-c-terminal-region-arp37738-t100.html |
Name |
MTA1 Antibody - C-terminal region (ARP37738_T100) |
Protein Size (# AA) |
430 amino acids |
Molecular Weight |
47kDa |
NCBI Gene Id |
9112 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
1.0 mg/ml |
Gene Full Name |
Metastasis associated 1 |
Peptide Sequence |
Synthetic peptide located within the following region: MPSRGLANHGQARHMGPSRNLLLNGKSYPTKVRLIRGGSLPPVKRRRMNW |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reference |
Kumar,R., et al., (2002) Nature 418 (6898), 654-658 |
Description of Target |
MTA1 encodes a protein that was identified in a screen for genes expressed in metastatic cells, specifically, mammary adenocarcinoma cell lines. Expression of this gene has been correlated with the metastatic potential of at least two types of carcinomas although it is also expressed in many normal tissues. The role it plays in metastasis is unclear. MTA1 was initially thought to be the 70kD component of a nucleosome remodeling deacetylase complex, NuRD, but it is more likely that this component is a different but very similar protein. These two proteins are so closely related, though, that they share the same types of domains. These domains include two DNA binding domains, a dimerization domain, and a domain commonly found in proteins that methylate DNA. The profile and activity of this gene product suggest that it is involved in regulating transcription and that this may be accomplished by chromatin remodeling. |
Protein Interactions |
KRT40; LZTS2; IKZF1; SH3GL1; SAT1; RBBP4; MAGEA11; KPNA3; NOTCH2NL; KRTAP10-8; KHDRBS2; SUMO2; SUMO3; DNMT3B; DNMT1; NACC2; UBC; SUZ12; EED; RNF2; HIC1; SOX2; HDAC2; HDAC1; HIST3H3; GATAD2B; MBD3; KDM1A; POLD3; MTA2; NR2C2; NR2C1; CHD4; UBE2I; HIST2H3C; B |
Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Datasheets/Manuals |
Printable datasheet for anti-MTA1 (ARP37738_T100) antibody |
Blocking Peptide |
For anti-MTA1 (ARP37738_T100) antibody is Catalog # AAP37738 (Previous Catalog # AAPP08820) |
Immunogen |
The immunogen is a synthetic peptide directed towards the C terminal region of human MTA1 |
Uniprot ID |
Q13330-2 |
Protein Name |
Metastasis-associated protein MTA1 |
Sample Type Confirmation |
MTA1 is strongly supported by BioGPS gene expression data to be expressed in Jurkat |
Protein Accession # |
AAN01613 |
Purification |
Protein A purified |
Nucleotide Accession # |
NM_001203258 |
Tested Species Reactivity |
Human |
Gene Symbol |
MTA1 |
Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit |
Application |
WB |
Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100% |
Image 1 | Human Jurkat
| WB Suggested Anti-MTA1 Antibody Titration: 2.5ug/ml ELISA Titer: 1:62500 Positive Control: Jurkat cell lysateMTA1 is strongly supported by BioGPS gene expression data to be expressed in Human Jurkat cells |
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