DHX16 Antibody - N-terminal region (ARP37711_P050)

Data Sheet
 
Product Number ARP37711_P050
Product Page www.avivasysbio.com/dhx16-antibody-n-terminal-region-arp37711-p050.html
Name DHX16 Antibody - N-terminal region (ARP37711_P050)
Protein Size (# AA) 1041 amino acids
Molecular Weight 115kDa
NCBI Gene Id 8449
Host Rabbit
Clonality Polyclonal
Concentration 0.5 mg/ml
Gene Full Name DEAH (Asp-Glu-Ala-His) box polypeptide 16
Alias Symbols DBP2, PRP8, Prp2, DDX16, NMOAS, PRPF2, PRO2014
Peptide Sequence Synthetic peptide located within the following region: KYQLVLEEEETIEFVRATQLQGDEEPSAPPTSTQAQQKESIQAVRRSLPV
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reference Beausoleil,S.A., et al., (2004) Proc. Natl. Acad. Sci. U.S.A. 101 (33), 12130-12135
Description of Target DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is a functional homolog of fission yeast Prp8 protein involved in cell cycle progression. This gene is mapped to the MHC region on chromosome 6p21.3, a region where many malignant, genetic and autoimmune disease genes are linked.
Protein Interactions NUDCD1; UBC; GPKOW; SF3B2; DHX38; DGCR14; CSNK2A1; XAB2; HELQ; PYROXD1; NAA40; LSM2; MIF4GD; GON4L; WDR44; EHD2; LSM5; LSM6; GCC2; TCEA2; MTR; GSPT1; GABPB1; APP; COIL; SNRNP27; SNRNP40; SIRT7; MEGF10; Bud13; TADA2A; SRRM2; SRRM1;
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for anti-DHX16 (ARP37711_P050) antibody
Blocking Peptide For anti-DHX16 (ARP37711_P050) antibody is Catalog # AAP37711 (Previous Catalog # AAPP09043)
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human DHX16
Uniprot ID O60231
Protein Name Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16
Sample Type Confirmation

DHX16 is supported by BioGPS gene expression data to be expressed in Jurkat

Protein Accession # NP_003578
Purification Affinity Purified
Nucleotide Accession # NM_003587
Tested Species Reactivity Human
Gene Symbol DHX16
Predicted Species Reactivity Human, Mouse, Rat, Cow, Goat, Horse, Pig, Rabbit
Application WB
Predicted Homology Based on Immunogen Sequence Cow: 86%; Goat: 86%; Horse: 86%; Human: 100%; Mouse: 79%; Pig: 85%; Rabbit: 77%; Rat: 79%
Image 1
Human Jurkat
WB Suggested Anti-DHX16 Antibody Titration: 0.125ug/ml
ELISA Titer: 1:62500
Positive Control: Jurkat cell lysateDHX16 is supported by BioGPS gene expression data to be expressed in Jurkat
 

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