Product Number |
ARP36921_T100 |
Product Page |
www.avivasysbio.com/mesp2-antibody-c-terminal-region-arp36921-t100.html |
Name |
MESP2 Antibody - C-terminal region (ARP36921_T100) |
Protein Size (# AA) |
370 amino acids |
Molecular Weight |
41kDa |
NCBI Gene Id |
17293 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
1.0 mg/ml |
Gene Full Name |
Mesoderm posterior 2 |
Alias Symbols |
bHLHc, bHLHc6 |
Peptide Sequence |
Synthetic peptide located within the following region: SCQRLQPQPQPQPQWGCWGHDAEVLSTSEDQGSSPALQLPVASPTPSSGL |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reference |
Morimoto,M., et al., (2005) Nature 435 (7040), 354-359 |
Description of Target |
Somite boundaries formed during embryogenesis, at the interface between Notch1-activated and -repressed domains. Genetic and biochemical studies indicate that this interface is generated by suppression of Notch activity by mesoderm posterior 2 (Mesp2) through induction of the lunatic fringe gene (Lfng). It is proposed that the oscillation of Notch activity is arrested and translated in the wavefront by Mesp2. |
Protein Interactions |
Lfng; |
Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Datasheets/Manuals |
Printable datasheet for anti-MESP2 (ARP36921_T100) antibody |
Blocking Peptide |
For anti-MESP2 (ARP36921_T100) antibody is Catalog # AAP36921 (Previous Catalog # AAPP08968) |
Immunogen |
The immunogen is a synthetic peptide directed towards the C terminal region of mouse MESP2 |
Uniprot ID |
O08574 |
Protein Name |
Mesoderm posterior protein 2 |
Publications |
Leschik, J., Stefanovic, S., Brinon, B. & Pucéat, M. Cardiac commitment of primate embryonic stem cells. Nat. Protoc. 3, 1381-7 (2008). 18772864 |
Protein Accession # |
NP_032615 |
Purification |
Protein A purified |
Nucleotide Accession # |
NM_008589 |
Tested Species Reactivity |
Mouse |
Gene Symbol |
MESP2 |
Predicted Species Reactivity |
Mouse, Rat |
Application |
WB |
Predicted Homology Based on Immunogen Sequence |
Mouse: 100%; Rat: 93% |
Image 1 | Mouse SP2/0
| WB Suggested Anti-MESP2 Antibody Titration: 1.25ug/ml ELISA Titer: 1:62500 Positive Control: SP2/0 cell lysate |
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