MESP2 Antibody - C-terminal region (ARP36921_T100)

Data Sheet
 
Product Number ARP36921_T100
Product Page www.avivasysbio.com/mesp2-antibody-c-terminal-region-arp36921-t100.html
Name MESP2 Antibody - C-terminal region (ARP36921_T100)
Protein Size (# AA) 370 amino acids
Molecular Weight 41kDa
NCBI Gene Id 17293
Host Rabbit
Clonality Polyclonal
Concentration 1.0 mg/ml
Gene Full Name Mesoderm posterior 2
Alias Symbols bHLHc, bHLHc6
Peptide Sequence Synthetic peptide located within the following region: SCQRLQPQPQPQPQWGCWGHDAEVLSTSEDQGSSPALQLPVASPTPSSGL
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reference Morimoto,M., et al., (2005) Nature 435 (7040), 354-359
Description of Target Somite boundaries formed during embryogenesis, at the interface between Notch1-activated and -repressed domains. Genetic and biochemical studies indicate that this interface is generated by suppression of Notch activity by mesoderm posterior 2 (Mesp2) through induction of the lunatic fringe gene (Lfng). It is proposed that the oscillation of Notch activity is arrested and translated in the wavefront by Mesp2.
Protein Interactions Lfng;
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for anti-MESP2 (ARP36921_T100) antibody
Blocking Peptide For anti-MESP2 (ARP36921_T100) antibody is Catalog # AAP36921 (Previous Catalog # AAPP08968)
Immunogen The immunogen is a synthetic peptide directed towards the C terminal region of mouse MESP2
Uniprot ID O08574
Protein Name Mesoderm posterior protein 2
Publications

Leschik, J., Stefanovic, S., Brinon, B. & Pucéat, M. Cardiac commitment of primate embryonic stem cells. Nat. Protoc. 3, 1381-7 (2008). 18772864

Protein Accession # NP_032615
Purification Protein A purified
Nucleotide Accession # NM_008589
Tested Species Reactivity Mouse
Gene Symbol MESP2
Predicted Species Reactivity Mouse, Rat
Application WB
Predicted Homology Based on Immunogen Sequence Mouse: 100%; Rat: 93%
Image 1
Mouse SP2/0
WB Suggested Anti-MESP2 Antibody Titration: 1.25ug/ml
ELISA Titer: 1:62500
Positive Control: SP2/0 cell lysate
 

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