ARX Antibody - middle region (ARP36824_T100)

Data Sheet
 
Product Number ARP36824_T100
Product Page www.avivasysbio.com/arx-antibody-middle-region-arp36824-t100.html
Name ARX Antibody - middle region (ARP36824_T100)
Protein Size (# AA) 564 amino acids
Molecular Weight 58kDa
NCBI Gene Id 11878
Host Rabbit
Clonality Polyclonal
Concentration 1.0 mg/ml
Gene Full Name Aristaless related homeobox
Alias Symbols Ar, Arx1
Peptide Sequence Synthetic peptide located within the following region: TGAEDDEEELLEDEEDEEEEEELLEDDDEELLEDDARALLKEPRRCSVAT
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reference Hirata,T., et al., (2006) Development 133 (8), 1433-1443
Description of Target ARX (Aristaless-related genes), a subset of the Paired-related homeobox genes, is a group of regulators of essential events during vertebrate embryogenesis. Arx was highly conserved between mouse and zebrafish. Studies have disclosed its neuromeric expression in the forebrain and longitudinal expression in the floor plate in mouse and zebrafish. It is also expressed in the dorsal telencephalon (presumptive cerebral cortex) of mouse embryos.
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for anti-ARX (ARP36824_T100) antibody
Blocking Peptide For anti-ARX (ARP36824_T100) antibody is Catalog # AAP36824 (Previous Catalog # AAPP09069)
Immunogen The immunogen is a synthetic peptide directed towards the middle region of mouse ARX
Uniprot ID O35085
Protein Name Homeobox protein ARX
Publications

Condomines, M. et al. Gene expression profiling and real-time PCR analyses identify novel potential cancer-testis antigens in multiple myeloma. J. Immunol. 183, 832-40 (2009). 19542363

Price, M. G. et al. A triplet repeat expansion genetic mouse model of infantile spasms syndrome, Arx(GCG)10+7, with interneuronopathy, spasms in infancy, persistent seizures, and adult cognitive and behavioral impairment. J. Neurosci. 29, 8752-63 (2009). 19587282

Protein Accession # NP_031518
Purification Protein A purified
Nucleotide Accession # NM_007492
Tested Species Reactivity Human, Mouse
Gene Symbol ARX
Predicted Species Reactivity Human, Mouse, Rat, Dog, Guinea Pig, Horse, Rabbit
Application WB
Predicted Homology Based on Immunogen Sequence Dog: 93%; Guinea Pig: 93%; Horse: 79%; Human: 93%; Mouse: 100%; Rabbit: 93%; Rat: 93%
Image 1
Human Fetal Heart
Host: Rabbit
Target Name: ARX
Sample Tissue: Human Fetal Heart
Antibody Dilution: 1.0ug/ml
 

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