Product Number |
ARP36824_T100 |
Product Page |
www.avivasysbio.com/arx-antibody-middle-region-arp36824-t100.html |
Name |
ARX Antibody - middle region (ARP36824_T100) |
Protein Size (# AA) |
564 amino acids |
Molecular Weight |
58kDa |
NCBI Gene Id |
11878 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
1.0 mg/ml |
Gene Full Name |
Aristaless related homeobox |
Alias Symbols |
Ar, Arx1 |
Peptide Sequence |
Synthetic peptide located within the following region: TGAEDDEEELLEDEEDEEEEEELLEDDDEELLEDDARALLKEPRRCSVAT |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reference |
Hirata,T., et al., (2006) Development 133 (8), 1433-1443 |
Description of Target |
ARX (Aristaless-related genes), a subset of the Paired-related homeobox genes, is a group of regulators of essential events during vertebrate embryogenesis. Arx was highly conserved between mouse and zebrafish. Studies have disclosed its neuromeric expression in the forebrain and longitudinal expression in the floor plate in mouse and zebrafish. It is also expressed in the dorsal telencephalon (presumptive cerebral cortex) of mouse embryos. |
Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Datasheets/Manuals |
Printable datasheet for anti-ARX (ARP36824_T100) antibody |
Blocking Peptide |
For anti-ARX (ARP36824_T100) antibody is Catalog # AAP36824 (Previous Catalog # AAPP09069) |
Immunogen |
The immunogen is a synthetic peptide directed towards the middle region of mouse ARX |
Uniprot ID |
O35085 |
Protein Name |
Homeobox protein ARX |
Publications |
Condomines, M. et al. Gene expression profiling and real-time PCR analyses identify novel potential cancer-testis antigens in multiple myeloma. J. Immunol. 183, 832-40 (2009). 19542363
Price, M. G. et al. A triplet repeat expansion genetic mouse model of infantile spasms syndrome, Arx(GCG)10+7, with interneuronopathy, spasms in infancy, persistent seizures, and adult cognitive and behavioral impairment. J. Neurosci. 29, 8752-63 (2009). 19587282 |
Protein Accession # |
NP_031518 |
Purification |
Protein A purified |
Nucleotide Accession # |
NM_007492 |
Tested Species Reactivity |
Human, Mouse |
Gene Symbol |
ARX |
Predicted Species Reactivity |
Human, Mouse, Rat, Dog, Guinea Pig, Horse, Rabbit |
Application |
WB |
Predicted Homology Based on Immunogen Sequence |
Dog: 93%; Guinea Pig: 93%; Horse: 79%; Human: 93%; Mouse: 100%; Rabbit: 93%; Rat: 93% |
Image 1 | Human Fetal Heart
| Host: Rabbit Target Name: ARX Sample Tissue: Human Fetal Heart Antibody Dilution: 1.0ug/ml |
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