| Product Number |
ARP36654_T100 |
| Product Page |
www.avivasysbio.com/mcm5-antibody-n-terminal-region-arp36654-t100.html |
| Name |
MCM5 Antibody - N-terminal region (ARP36654_T100) |
| Protein Size (# AA) |
734 amino acids |
| Molecular Weight |
82kDa |
| NCBI Gene Id |
4174 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
1.0 mg/ml |
| Gene Full Name |
Minichromosome maintenance complex component 5 |
| Alias Symbols |
CDC46, MGORS8, P1-CDC46 |
| Peptide Sequence |
Synthetic peptide located within the following region: MSGFDDPGIFYSDSFGGDAQADEGQARKSQLQRRFKEFLRQYRVGTDRTG |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Ohtani,K., et al., (1999) Oncogene 18 (14), 2299-2309 |
| Description of Target |
The protein encoded by MCM5 is structurally very similar to the CDC46 protein from S. cerevisiae, a protein involved in the initiation of DNA replication. The encoded protein is a member of the MCM family of chromatin-binding proteins and can interact with at least two other members of this family. The encoded protein is upregulated in the transition from the G0 to G1/S phase of the cell cycle and may actively participate in cell cycle regulation. |
| Protein Interactions |
KRTAP10-7; RBPMS; SUMO2; SUMO3; MCMBP; UBC; RNF2; NEK9; MCM3; HSP90AB1; HSP90AA1; FKBP5; MAGED2; CAP1; BAG3; CD81; IGSF8; TCEA1; PNKP; VCAM1; ORC5; ORC1; MCM7; MCM2; ITGA4; FN1; CDKN2A; CDC5L; NOTCH1; MYBBP1A; U2AF1; MCM6; MCM4; HNRNPU; APP; FBXO6; NEDD8; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-MCM5 (ARP36654_T100) antibody |
| Blocking Peptide |
For anti-MCM5 (ARP36654_T100) antibody is Catalog # AAP36654 (Previous Catalog # AAPP07911) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human MCM5 |
| Uniprot ID |
P33992 |
| Protein Name |
DNA replication licensing factor MCM5 |
| Protein Accession # |
NP_006730 |
| Purification |
Protein A purified |
| Nucleotide Accession # |
NM_006739 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
MCM5 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Horse, Rabbit |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 86%; Horse: 86%; Human: 100%; Mouse: 79%; Rabbit: 86%; Rat: 79% |
| Image 1 | Human HepG2
 | WB Suggested Anti-MCM5 Antibody Titration: 2.5ug/ml
ELISA Titer: 1:62500
Positive Control: HepG2 cell lysate |
|
