| Product Number |
ARP36584_T100 |
| Product Page |
www.avivasysbio.com/anxa7-antibody-n-terminal-region-arp36584-t100.html |
| Name |
ANXA7 Antibody - N-terminal region (ARP36584_T100) |
| Protein Size (# AA) |
466 amino acids |
| Molecular Weight |
51kDa |
| NCBI Gene Id |
310 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
1.0 mg/ml |
| Gene Full Name |
Annexin A7 |
| Alias Symbols |
SNX, ANX7, SYNEXIN |
| Peptide Sequence |
Synthetic peptide located within the following region: MSYPGYPPTGYPPFPGYPPAGQESSFPPSGQYPYPSGFPPMGGGAYPQVP |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Satoh,H., et al., (2002) Biochim. Biophys. Acta 1600 (1-2), 61-67 |
| Description of Target |
ANXA7 is a member of the annexin family of calcium-dependent phospholipid binding proteins. The Annexin VII gene contains 14 exons and spans approximately 34 kb of DNA. An alternatively spliced cassette exon results in two mRNA transcripts of 2.0 and 2.4 kb which are predicted to generate two protein isoforms differing in their N-terminal domain. The alternative splicing event is tissue specific and the mRNA containing the cassette exon is prevalent in brain, heart and skeletal muscle. The transcripts also differ in their 3'-non coding regions by the use of two alternative poly(A) signals. The selection of poly(A) signals is independent of the mRNA splicing pattern. Annexin VII encodes a protein with a molecular weight of approximately 51 kDa with a unique, highly hydrophobic N-terminal domain of 167 amino acids and a conserved C-terminal region of 299 amino acids. The latter domain is composed of alternating hydrophobic and hydrophilic segments. Structural analysis of the protein suggests that Annexin VII is a membrane binding protein with diverse properties including voltage-sensitive calcium channel activity, ion selectivity and membrane fusion. |
| Protein Interactions |
UBC; PAX8; ATP4A; SRC; Prkcb; Prkcg; Prkca; PRKG1; PRKACA; VCP; ANXA4; CUL4B; CUL5; ALG2; ELAVL1; CCDC90B; WDR18; LRIF1; OTUB1; CPSF3L; SEMA5B; INPP5K; ACTL6B; CSAD; SDF4; MED31; TAF5L; TRMT2A; TUBB2B; CPNE2; ZNF431; KLHL23; DOCK7; WDR73; FBN3; RBM48; ADA |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-ANXA7 (ARP36584_T100) antibody |
| Blocking Peptide |
For anti-ANXA7 (ARP36584_T100) antibody is Catalog # AAP36584 (Previous Catalog # AAPP07817) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human ANXA7 |
| Uniprot ID |
Q5T0M6 |
| Protein Name |
Annexin A7 |
| Protein Accession # |
NP_001147 |
| Purification |
Protein A purified |
| Nucleotide Accession # |
NM_001156 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
ANXA7 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 86%; Dog: 93%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 86%; Rabbit: 93%; Rat: 100% |
| Image 1 | Human Placenta
 | WB Suggested Anti-ANXA7 Antibody Titration: 2.5ug/ml
ELISA Titer: 1:312500
Positive Control: Human Placenta |
| | Image 2 | Human 786-0 Whole Cell
 | Host: Rabbit
Target Name: ANXA7
Sample Tissue: Human 786-0 Whole Cell
Antibody Dilution: 1ug/ml |
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