| Product Number |
ARP36470_P050 |
| Product Page |
www.avivasysbio.com/wrnip1-antibody-n-terminal-region-arp36470-p050.html |
| Name |
WRNIP1 Antibody - N-terminal region (ARP36470_P050) |
| Protein Size (# AA) |
640 amino acids |
| Molecular Weight |
72kDa |
| NCBI Gene Id |
56897 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
Werner helicase interacting protein 1 |
| Alias Symbols |
WHIP, FAP93, CFAP93, bA420G6.2 |
| Peptide Sequence |
Synthetic peptide located within the following region: PGAKRRRLSESSALKQPATPTAAESSEGEGEEGDDGGETESRESYDAPPT |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Tsurimoto,T., et al., (2005) Genes Cells 10 (1), 13-22 |
| Description of Target |
Werner's syndrome is a rare autosomal recessive disorder characterized by premature aging. The protein encoded by this gene interacts with the N-terminal portion of Werner protein containing the exonuclease domain. This protein shows homology to replication factor C family proteins, and is conserved from E. coli to human. Studies in yeast suggest that this gene may influence the aging process. Two transcript variants encoding different isoforms have been isolated for this gene.Werner's syndrome is a rare autosomal recessive disorder characterized by premature aging. The protein encoded by this gene interacts with the N-terminal portion of Werner protein containing the exonuclease domain. This protein shows homology to replication factor C family proteins, and is conserved from E. coli to human. Studies in yeast suggest that this gene may influence the aging process. Two transcript variants encoding different isoforms have been isolated for this gene. |
| Protein Interactions |
UBC; RNF31; PIN1; ELP2; ELP3; TRIM28; HDAC11; EPAS1; VCP; SRSF4; SMAD2; RAD18; NUP107; WRNIP1; FGFR1OP; POLD1; ABL1; SUMO2; TOLLIP; DDX58; USP11; OSBPL10; USP25; POLD4; POLD2; WRN; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-WRNIP1 (ARP36470_P050) antibody |
| Blocking Peptide |
For anti-WRNIP1 (ARP36470_P050) antibody is Catalog # AAP36470 (Previous Catalog # AAPP08529) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human WRNIP1 |
| Uniprot ID |
Q96S55 |
| Protein Name |
ATPase WRNIP1 |
| Protein Accession # |
NP_569079 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_130395 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
WRNIP1 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Pig, Yeast, Zebrafish |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 79%; Dog: 100%; Human: 100%; Mouse: 100%; Pig: 79%; Rat: 100%; Yeast: 77%; Zebrafish: 85% |
| Image 1 | Human HepG2
 | WB Suggested Anti-WRNIP1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: HepG2 cell lysate |
|
| Image 2 | Human
 | Sample Type: HeLa cell lysateDilution: 1:1000 |
|
