| Product Number |
ARP35751_T100 |
| Product Page |
www.avivasysbio.com/tbpl1-antibody-middle-region-arp35751-t100.html |
| Name |
TBPL1 Antibody - middle region (ARP35751_T100) |
| Protein Size (# AA) |
186 amino acids |
| Molecular Weight |
21kDa |
| NCBI Gene Id |
9519 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
1.0 mg/ml |
| Gene Full Name |
TBP-like 1 |
| Alias Symbols |
TLF, TLP, STUD, TRF2, MGC:8389, MGC:9620 |
| Peptide Sequence |
Synthetic peptide located within the following region: LQKLGFQVIFTDFKVVNVLAVCNMPFEIRLPEFTKNNRPHASYEPELHPA |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Martianov,I., et al., (2002) Development 129 (4), 945-955 |
| Description of Target |
Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TBPL1 encodes a protein that serves the same function as TBP and substitutes for TBP at some promoters that are not recognized by TFIID. It is essential for spermiogenesis and believed to be important in expression of developmentally regulated genes. |
| Protein Interactions |
TNNT1; FUS; APP; PRNP; ELAVL1; UBC; TERF2; TERF1; TBPL2; TAF1L; TBP; TAF6; TAF5; TAF4; TAF1; HSPA9; GTF2A2; GTF2A1; SLC35F6; ABCF3; NDUFA6; GTF2B; PTCD3; IRAK4; RAB35; PLIN3; RPL10; NF1; PMVK; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-TBPL1 (ARP35751_T100) antibody |
| Blocking Peptide |
For anti-TBPL1 (ARP35751_T100) antibody is Catalog # AAP35751 (Previous Catalog # AAPP07003) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the middle region of human TBPL1 |
| Uniprot ID |
P62380 |
| Protein Name |
TATA box-binding protein-like protein 1 |
| Protein Accession # |
NP_004856 |
| Purification |
Protein A purified |
| Nucleotide Accession # |
NM_004865 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
TBPL1 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish |
| Application |
IHC, WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 92% |
| Image 1 | Human HepG2
 | WB Suggested Anti-TBPL1 Antibody Titration: 1.25ug/ml
ELISA Titer: 1:312500
Positive Control: HepG2 cell lysate |
|
| Image 2 | Human kidney
 | Human kidney |
|
