Product Number |
ARP35724_T100 |
Product Page |
www.avivasysbio.com/trip13-antibody-n-terminal-region-arp35724-t100.html |
Name |
TRIP13 Antibody - N-terminal region (ARP35724_T100) |
Protein Size (# AA) |
432 amino acids |
Molecular Weight |
49kDa |
NCBI Gene Id |
9319 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
1.0 mg/ml |
Gene Full Name |
Thyroid hormone receptor interactor 13 |
Alias Symbols |
MVA3, OOMD9, 16E1BP |
Peptide Sequence |
Synthetic peptide located within the following region: KDSQPIDLSACTVALHIFQLNEDGPSSENLEEETENIIAANHWVLPAAEF |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reference |
Rual,J.F., et al., (2005) Nature 437 (7062), 1173-1178 |
Description of Target |
The thyroid hormone (T3) receptors (TRs) are hormone-dependent transcription factors that regulate expression of a variety of specific target genes. TRIP13 specifically interacts with the ligand binding domain of the TRs. It is a member of Trips (TR-interacting proteins) family. Nearly all of the Trips also show similar ligand-dependent interaction with the retinoid X receptor (RXR), but none interact with the glucocorticoid receptor under any conditions. Trips predict specific functional roles: one is an apparent human homolog of a yeast transcriptional coactivator, one is a new member of a class of nonhistone chromosomal proteins, and one contains a conserved domain associated with ubiquitination of specific target proteins. |
Protein Interactions |
KRTAP26-1; KRTAP12-1; KRTAP12-2; MORN3; TEX37; METTL15; MGAT5B; C4orf33; GLYCTK; M1AP; LRR1; LNX1; RHOXF2; LOXL4; ZNF34; FNDC3B; TINAGL1; PBLD; SEMA4G; SPRYD7; PELI1; PLSCR3; PCMTD2; CYB5R2; AMDHD2; TNRC6A; DIP2A; DPYSL4; TRIP13; SIGLEC5; TPT1; SCP2; QARS |
Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Datasheets/Manuals |
Printable datasheet for anti-TRIP13 (ARP35724_T100) antibody |
Blocking Peptide |
For anti-TRIP13 (ARP35724_T100) antibody is Catalog # AAP35724 (Previous Catalog # AAPP06970) |
Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human TRIP13 |
Uniprot ID |
Q15645 |
Protein Name |
Pachytene checkpoint protein 2 homolog |
Sample Type Confirmation |
TRIP13 is supported by BioGPS gene expression data to be expressed in Jurkat |
Protein Accession # |
NP_004228 |
Purification |
Protein A purified |
Nucleotide Accession # |
NM_004237 |
Tested Species Reactivity |
Human |
Gene Symbol |
TRIP13 |
Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit |
Application |
IHC, WB |
Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 79%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 93%; Rabbit: 100%; Rat: 93% |
Image 1 | Human Jurkat
| WB Suggested Anti-TRIP13 Antibody Titration: 5.0ug/ml ELISA Titer: 1:12500 Positive Control: Jurkat cell lysateTRIP13 is supported by BioGPS gene expression data to be expressed in Jurkat |
|
Image 2 | Human Heart
| Rabbit Anti-TRIP13 antibody Catalog Number: ARP35724_T100 Paraffin Embedded Tissue: Human Heart cell Cellular Data: Epithelial cells of renal tubule Antibody Concentration: 4.0-8.0 ug/ml Magnification: 400X |
|