| Product Number |
ARP35721_T100 |
| Product Page |
www.avivasysbio.com/klf4-antibody-n-terminal-region-arp35721-t100.html |
| Name |
KLF4 Antibody - N-terminal region (ARP35721_T100) |
| Protein Size (# AA) |
470 amino acids |
| Molecular Weight |
50kDa |
| NCBI Gene Id |
9314 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
1.0 mg/ml |
| Gene Full Name |
Kruppel-like factor 4 (gut) |
| Alias Symbols |
EZF, GKLF |
| Peptide Sequence |
Synthetic peptide located within the following region: GAACGGSNLAPLPRRETEEFNDLLDLDFILSNSLTHPPESVAATVSSSAS |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Yoon,H.S., (2005) Oncogene 24 (25), 4017-4025 |
| Description of Target |
The mammalian Kruppel-like transcription factor, KLF4 is involved in preventing centrosome amplification following DNA damage caused by gamma-irradiation. It is both necessary and sufficient in preventing centrosome amplification following gamma-radiation-induced DNA damage and does so by transcriptionally suppressing cyclin E expression n. Kruppel-like factor 4 is also known to exhibit checkpoint function during the G1/S and G2/M transitions of the cell cycle. |
| Protein Interactions |
EP300; CREBBP; SETD7; CTBP1; Dlg4; APP; CUL2; VHL; UBC; TCEB2; SP1; RELA; PRKCD; PPARG; SMARCA4; HDAC2; HDAC7; KAT5; HDAC1; HDAC5; ELK1; KLF6; TP53; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-KLF4 (ARP35721_T100) antibody |
| Blocking Peptide |
For anti-KLF4 (ARP35721_T100) antibody is Catalog # AAP35721 (Previous Catalog # AAPP06967) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human KLF4 |
| Uniprot ID |
O43474 |
| Protein Name |
Krueppel-like factor 4 |
| Protein Accession # |
NP_004226 |
| Purification |
Protein A purified |
| Nucleotide Accession # |
NM_004235 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
KLF4 |
| Predicted Species Reactivity |
Human, Cow, Dog, Horse, Pig, Rabbit, Sheep |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 80%; Dog: 87%; Horse: 87%; Human: 100%; Pig: 80%; Rabbit: 85%; Sheep: 80% |
| Image 1 | Transfected 293T
 | WB Suggested Anti-KLF4 Antibody Titration: 2.5ug/ml
ELISA Titer: 1:312500
Positive Control: Transfected 293T |
|
| Image 2 | Human lung cell line
 | Human lung cell line |
|
