Product Number |
ARP35515_T100 |
Product Page |
www.avivasysbio.com/grik2-antibody-n-terminal-region-arp35515-t100.html |
Name |
GRIK2 Antibody - N-terminal region (ARP35515_T100) |
Protein Size (# AA) |
908 amino acids |
Molecular Weight |
102kDa |
NCBI Gene Id |
2898 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
1.0 mg/ml |
Gene Full Name |
Glutamate receptor, ionotropic, kainate 2 |
Alias Symbols |
EAA4, GLR6, MRT6, GLUK6, GLUR6, GluK2 |
Peptide Sequence |
Synthetic peptide located within the following region: PDFSSLSRAILDLVQFFKWKTVTVVYDDSTGLIRLQELIKAPSRYNLRLK |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reference |
Delorme,R., et al., (2004) 15 (4), 699-702 |
Description of Target |
The GRIK2 gene encodes a subunit of a kainate glutamate receptor. Glutamate receptors mediate the majority of excitatory neurotransmission in the brain. This receptor may have a role in synaptic plasticity and may be important for learning and memory. It also may be involved in the transmission of light information from the retina to the hypothalamus. The structure and function of the encoded protein is changed by RNA editing. |
Protein Interactions |
CALCOCO1; TRIM25; PICK1; DLG4; LIN7B; GRID2; PRKAA1; SDCBP; CTNND1; DLG1; GRIK5; GRIK4; DLG3; CASK; GRIA1; GRIK2; CTNNB1; CDH2; GRIP1; GRIA2; |
Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Datasheets/Manuals |
Printable datasheet for anti-GRIK2 (ARP35515_T100) antibody |
Blocking Peptide |
For anti-GRIK2 (ARP35515_T100) antibody is Catalog # AAP35515 (Previous Catalog # AAPP07288) |
Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human GRIK2 |
Uniprot ID |
Q13002 |
Protein Name |
Glutamate receptor, ionotropic kainate 2 |
Publications |
Funk, J. A. et al. Characterization of renal toxicity in mice administered the marine biotoxin domoic Acid. J. Am. Soc. Nephrol. 25, 1187-97 (2014). 24511141 |
Purification |
Protein A purified |
Tested Species Reactivity |
Human, Mouse |
Gene Symbol |
GRIK2 |
Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish |
Application |
IHC, WB |
Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100% |
Image 1 | Human kidney
| Human kidney |
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Image 2 | Human Jurkat
| WB Suggested Anti-GRIK2 Antibody Titration: 1.25ug/ml ELISA Titer: 1:1562500 Positive Control: Jurkat cell lysate |
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Image 3 | Mouse cortex brain
| Lanes: Lane1: 10ug mouse cortex brain lysate Lane2: 25ug mouse cortex brain lysate Lane3: 40ug mouse cortex brain lysate Primary Antibody Dilution: 1:1000 Secondary Antibody: Anti-rabbit HRP Secondary Antibody Dilution: 1:2000 Gene Name: GRIK2 Submitted by: Anonymous
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