GRIK2 Antibody - N-terminal region (ARP35515_T100)

Data Sheet
 
Product Number ARP35515_T100
Product Page www.avivasysbio.com/grik2-antibody-n-terminal-region-arp35515-t100.html
Name GRIK2 Antibody - N-terminal region (ARP35515_T100)
Protein Size (# AA) 908 amino acids
Molecular Weight 102kDa
NCBI Gene Id 2898
Host Rabbit
Clonality Polyclonal
Concentration 1.0 mg/ml
Gene Full Name Glutamate receptor, ionotropic, kainate 2
Alias Symbols EAA4, GLR6, MRT6, GLUK6, GLUR6, GluK2
Peptide Sequence Synthetic peptide located within the following region: PDFSSLSRAILDLVQFFKWKTVTVVYDDSTGLIRLQELIKAPSRYNLRLK
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reference Delorme,R., et al., (2004) 15 (4), 699-702
Description of Target The GRIK2 gene encodes a subunit of a kainate glutamate receptor. Glutamate receptors mediate the majority of excitatory neurotransmission in the brain. This receptor may have a role in synaptic plasticity and may be important for learning and memory. It also may be involved in the transmission of light information from the retina to the hypothalamus. The structure and function of the encoded protein is changed by RNA editing.
Protein Interactions CALCOCO1; TRIM25; PICK1; DLG4; LIN7B; GRID2; PRKAA1; SDCBP; CTNND1; DLG1; GRIK5; GRIK4; DLG3; CASK; GRIA1; GRIK2; CTNNB1; CDH2; GRIP1; GRIA2;
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for anti-GRIK2 (ARP35515_T100) antibody
Blocking Peptide For anti-GRIK2 (ARP35515_T100) antibody is Catalog # AAP35515 (Previous Catalog # AAPP07288)
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human GRIK2
Uniprot ID Q13002
Protein Name Glutamate receptor, ionotropic kainate 2
Publications

Funk, J. A. et al. Characterization of renal toxicity in mice administered the marine biotoxin domoic Acid. J. Am. Soc. Nephrol. 25, 1187-97 (2014). 24511141

Purification Protein A purified
Tested Species Reactivity Human, Mouse
Gene Symbol GRIK2
Predicted Species Reactivity Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish
Application IHC, WB
Predicted Homology Based on Immunogen Sequence Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%
Image 1
Human kidney
Human kidney
Image 2
Human Jurkat
WB Suggested Anti-GRIK2 Antibody Titration: 1.25ug/ml
ELISA Titer: 1:1562500
Positive Control: Jurkat cell lysate
Image 3
Mouse cortex brain
Lanes:
Lane1: 10ug mouse cortex brain lysate
Lane2: 25ug mouse cortex brain lysate
Lane3: 40ug mouse cortex brain lysate
Primary Antibody Dilution:
1:1000
Secondary Antibody:
Anti-rabbit HRP
Secondary Antibody Dilution:
1:2000
Gene Name:
GRIK2
Submitted by:
Anonymous
 

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