Product Number |
ARP35045_T100 |
Product Page |
www.avivasysbio.com/clic1-antibody-n-terminal-region-arp35045-t100.html |
Name |
CLIC1 Antibody - N-terminal region (ARP35045_T100) |
Protein Size (# AA) |
241 amino acids |
Molecular Weight |
27 kDa |
NCBI Gene Id |
1192 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
1.0 mg/ml |
Gene Full Name |
Chloride intracellular channel 1 |
Alias Symbols |
G6, CL1C1, NCC27, CLCNL1 |
Peptide Sequence |
Synthetic peptide located within the following region: GQLPFLLYGTEVHTDTNKIEEFLEAVLCPPRYPKLAALNPESNTAGLDIF |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reference |
Novarino,G., et al., (2004) J. Neurosci. 24 (23), 5322-5330 |
Description of Target |
Chloride intracellular channel 1 is a member of the p64 family, a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. CLIon Channel1 encodes a protein that localizes principally to the cell nucleus and exhibits both nuclear and plasma membrane chloride ion channel activity. |
Protein Interactions |
UBC; PSMD10; SUMO2; SUMO1; NEDD8; FBXO6; ZNF302; NUP62; PRDX4; IKBKG; ZNF184; VCAM1; THRA; RPLP1; NTF4; ITGA4; FN1; ATF2; CPT1A; ATP6V0A1; ATP6V0C; ATP5F1; ALOX5AP; GRK5; MYOC; CDK2; ISG15; ARRB2; SUMO4; LSM1; AKAP9; TRAPPC2; |
Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Enhanced Validation |
Relative Expression (Western Blot) |
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Datasheets/Manuals |
Printable datasheet for anti-CLIC1 (ARP35045_T100) antibody |
Blocking Peptide |
For anti-CLIC1 (ARP35045_T100) antibody is Catalog # AAP35045 (Previous Catalog # AAPP06272) |
Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human CLIC1 |
Uniprot ID |
Q502X1 |
Protein Name |
Chloride intracellular channel protein 1 |
Publications |
Yang, J.-Y. et al. Chloride intracellular channel 1 regulates osteoblast differentiation. Bone 45, 1175-85 (2009). 19703605 |
Protein Accession # |
NP_001279 |
Purification |
Protein A purified |
Nucleotide Accession # |
NM_001288 |
Tested Species Reactivity |
Human, Mouse |
Gene Symbol |
CLIC1 |
Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit, Zebrafish |
Application |
IHC, WB |
Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Goat: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93% |
Image 1 | Human Jurkat
| WB Suggested Anti-CLIC1 Antibody Titration: 1.25ug/ml ELISA Titer: 1:312500 Positive Control: Jurkat cell lysate |
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Image 2 | Human kidney
| Human kidney |
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Image 3 | Mouse Pancreas
| Host: Mouse Target Name: CLIC1 Sample Tissue: Mouse Pancreas Antibody Dilution: 1ug/ml |
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Image 4 | Western Blot
| 25 ug of the indicated Human whole cell extracts was loaded onto a 12% SDS-PAGE gel. 1 ug/mL of the antibody was used in this experiment. |
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