CLIC1 Antibody - C-terminal region (ARP35044_T100)

• Product Number: ARP35044_T100
• Name: CLIC1 Antibody - C-terminal region (ARP35044_T100)
• Protein Size (# AA): 241 amino acids
• Molecular Weight: 27kDa
• NCBI Gene Id: 1192
• Host: Rabbit
• Clonality: Polyclonal
• Concentration: 1.0 mg/ml
• Gene Full Name: Chloride intracellular channel 1
• Alias Symbols: G6, CL1C1, NCC27, CLCNL1
• Peptide Sequence: Synthetic peptide located within the following region: LTLADCNLLPKLHIVQVVCKKYRGFTIPEAFRGVHRYLSNAYAREEFAST
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Reference: Bruneel,A., (2005) Proteomics 5 (15), 3876-3884
• Description of Target: Chloride intracellular channel 1 is a member of the p64 family, a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. CLIon Channel1 encodes a protein that localizes principally to the cell nucleus and exhibits both nuclear and plasma membrane chloride ion channel activity.Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. Chloride intracellular channel 1 is a member of the p64 family; the protein localizes principally to the cell nucleus and exhibits both nuclear and plasma membrane chloride ion channel activity.
• Protein Interactions: UBC; PSMD10; SUMO2; SUMO1; NEDD8; FBXO6; ZNF302; NUP62; PRDX4; IKBKG; ZNF184; VCAM1; THRA; RPLP1; NTF4; ITGA4; FN1; ATF2; CPT1A; ATP6V0A1; ATP6V0C; ATP5F1; ALOX5AP; GRK5; MYOC; CDK2; ISG15; ARRB2; SUMO4; LSM1; AKAP9; TRAPPC2;
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Blocking Peptide: For anti-CLIC1 (ARP35044_T100) antibody is Catalog # AAP35044
• Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CLIC1
• Uniprot ID: O00299
• Protein Name: Chloride intracellular channel protein 1
• Protein Accession #: NP_001279
• Purification: Protein A purified
• Nucleotide Accession #: NM_001288
• Tested Species Reactivity: Human, Mouse
• Gene Symbol: CLIC1
• Predicted Species Reactivity: Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit
• Application: WB
• Predicted Homology Based on Immunogen Sequence: Cow: 83%; Dog: 92%; Goat: 83%; Guinea Pig: 92%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%
• Image 1: Mouse renal epithelial
  
  Lanes:
  Lane 1: 30ug mouse renal epithelial lysate
  Lane 2: 30ug mouse renal epithelial lysate
  Lane 3: 30ug mouse renal epithelial lysate
  Primary Antibody Dilution:
  1:500
  Secondary Antibody:
  Anti-rabbit-HRP
  Secondary Antibody Dilution:
  1:2500
  Gene Name:
  CLIC1
  Submitted by:
  Dr. JUNMING FAN,ECU
  
• Image 2: Human
  
  CLIC1 antibody - C-terminal region (ARP35044_T100) validated by WB using purified recombinant CLIC1 protein and transfected lysate
• Image 3: Human
  
  Sample Type: Purified Recombinant CLIC-1 proteinPrimary Dilution: 1:1000