| Product Number |
ARP35016_P050 |
| Product Page |
www.avivasysbio.com/grin2c-antibody-n-terminal-region-arp35016-p050.html |
| Name |
GRIN2C Antibody - N-terminal region (ARP35016_P050) |
| Protein Size (# AA) |
1233 amino acids |
| Molecular Weight |
134 kDa |
| Subunit |
epsilon-3 |
| NCBI Gene Id |
2905 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
Glutamate receptor, ionotropic, N-methyl D-aspartate 2C |
| Alias Symbols |
NR2C, GluN2C, NMDAR2C |
| Peptide Sequence |
Synthetic peptide located within the following region: VNTTNPSSLLTQICGLLGAAHVHGIVFEDNVDTEAVAQILDFISSQTHVP |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Self,R.L., et al., (2004) Brain Res. 995 (1), 39-45 |
| Description of Target |
N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of the key receptor subunit NMDAR1 (GRIN1) and 1 or more of the 4 NMDAR2 subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C), and NMDAR2D (GRIN2D). |
| Protein Interactions |
ERBB2IP; DLGAP1; INADL; IL16; DLG4; DLG3; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Enhanced Validation |
| Relative Expression (Western Blot) |
 |
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| Datasheets/Manuals |
Printable datasheet for anti-GRIN2C (ARP35016_P050) antibody |
| Blocking Peptide |
For anti-GRIN2C (ARP35016_P050) antibody is Catalog # AAP35016 (Previous Catalog # AAPP06243) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human GRIN2C |
| Uniprot ID |
Q14957 |
| Protein Name |
Glutamate [NMDA] receptor subunit epsilon-3 |
| Sample Type Confirmation |
GRIN2C is supported by BioGPS gene expression data to be expressed in Jurkat |
| Protein Accession # |
NP_000826 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_000835 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
GRIN2C |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit, Zebrafish |
| Application |
WB, IHC |
| Predicted Homology Based on Immunogen Sequence |
Cow: 93%; Dog: 93%; Guinea Pig: 93%; Human: 100%; Mouse: 100%; Rabbit: 86%; Rat: 100%; Zebrafish: 79% |
| Image 1 | heart
 | Rabbit Anti-GRIN2C Antibody
Catalog Number: ARP35016_P050
Formalin Fixed Paraffin Embedded Tissue: Human Adult heart
Observed Staining: Membrane
Primary Antibody Concentration: 1:100
Secondary Antibody: Donkey anti-Rabbit-Cy2/3
Secondary Antibody Concentration: 1:200
Magnification: 20X
Exposure Time: 0.5 2.0 sec
Protocol located in Reviews and Data. |
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| Image 2 |
 | 25 ug of the indicated Human whole cell extracts was loaded onto a 6-18% SDS-PAGE gel. 1 ug/mL of the antibody was used in this experiment. The protein may be modified by glycosylation and phosphorylation.
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