CHRNA1 Antibody - N-terminal region (ARP34909_P050)

Data Sheet
 
Product Number ARP34909_P050
Product Page www.avivasysbio.com/chrna1-antibody-n-terminal-region-arp34909-p050.html
Name CHRNA1 Antibody - N-terminal region (ARP34909_P050)
Protein Size (# AA) 457 amino acids
Molecular Weight 52kDa
Subunit alpha
NCBI Gene Id 1134
Host Rabbit
Clonality Polyclonal
Concentration 0.5 mg/ml
Gene Full Name Cholinergic receptor, nicotinic, alpha 1 (muscle)
Alias Symbols ACHRA, ACHRD, CHRNA, CMS1A, CMS1B, CMS2A, FCCMS, SCCMS
Peptide Sequence Synthetic peptide located within the following region: TRLVAKLFKDYSSVVRPVEDHRQVVEVTVGLQLIQLINVDEVNQIVTTNV
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reference Webster,R., et al., (2004) Neurology 62 (7), 1090-1096
Description of Target The muscle acetylcholine receptor consiststs of 5 subunits of 4 different types: 2 alpha isoforms and 1 each of beta, gamma, and delta subunits.2 CHRNA1 encodes an alpha subunit that plays a role in acetlycholine binding/channel gating.
Protein Interactions ITGA7; CHRND; CHRNG; CHRNE;
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for anti-CHRNA1 (ARP34909_P050) antibody
Blocking Peptide For anti-CHRNA1 (ARP34909_P050) antibody is Catalog # AAP34909 (Previous Catalog # AAPP06133)
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human CHRNA1
Uniprot ID P02708-2
Protein Name Acetylcholine receptor subunit alpha
Protein Accession # NP_000070
Purification Affinity Purified
Nucleotide Accession # NM_000079
Tested Species Reactivity Human
Gene Symbol CHRNA1
Predicted Species Reactivity Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit
Application WB
Predicted Homology Based on Immunogen Sequence Cow: 93%; Dog: 93%; Guinea Pig: 86%; Horse: 93%; Human: 100%; Mouse: 79%; Pig: 93%; Rabbit: 93%; Rat: 93%
Image 1
Human Jurkat
WB Suggested Anti-CHRNA1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: Jurkat cell lysate
 

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