| Product Number |
ARP34884_P050 |
| Product Page |
www.avivasysbio.com/dido1-antibody-n-terminal-region-arp34884-p050.html |
| Name |
DIDO1 Antibody - N-terminal region (ARP34884_P050) |
| Protein Size (# AA) |
544 amino acids |
| Molecular Weight |
59kDa |
| NCBI Gene Id |
11083 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
Death inducer-obliterator 1 |
| Alias Symbols |
BYE1, DIO1, DATF1, DIDO2, DIDO3, DIO-1, DATF-1, C20orf158, dJ885L7.8 |
| Peptide Sequence |
Synthetic peptide located within the following region: ERVEQFLTIARRRGRRSMPVSLEDSGEPTSCPATDAETASEGSVESASET |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Futterer,A., et al., (2005) J. Clin. Invest. 115 (9), 2351-2362 |
| Description of Target |
In mice, the death inducer-obliterator-1 gene is upregulated by apoptotic signals and encodes a cytoplasmic protein that translocates to the nucleus upon apoptotic signal activation. When overexpressed, the mouse protein induced apoptosis in cell lines growing in vitro. DIDO1 gene is similar to the mouse gene and therefore is thought to be involved in apoptosis.Apoptosis, a major form of cell death, is an efficient mechanism for eliminating unwanted cells and is of central importance for development and homeostasis in metazoan animals. In mice, the death inducer-obliterator-1 gene is upregulated by apoptotic signals and encodes a cytoplasmic protein that translocates to the nucleus upon apoptotic signal activation. When overexpressed, the mouse protein induced apoptosis in cell lines growing in vitro. This gene is similar to the mouse gene and therefore is thought to be involved in apoptosis. Alternatively spliced transcripts have been found for this gene, encoding multiple isoforms. |
| Protein Interactions |
UBC; WWOX; RPA3; RPA2; RPA1; EED; BMI1; HECW2; SRPK2; KCNK4; ARAF; Dlg4; H2AFY; U2AF1; SON; RPL18A; KRT7; APP; PCDHA2; H2AFY2; GNL3; RRS1; SIRT7; SUMO2; WWP2; WWP1; DVL3; SRSF1; HNRNPK; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-DIDO1 (ARP34884_P050) antibody |
| Blocking Peptide |
For anti-DIDO1 (ARP34884_P050) antibody is Catalog # AAP34884 (Previous Catalog # AAPP06093) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human DIDO1 |
| Uniprot ID |
Q9BTC0-2 |
| Protein Name |
Death-inducer obliterator 1 |
| Sample Type Confirmation |
DIDO1 is strongly supported by BioGPS gene expression data to be expressed in Jurkat |
| Protein Accession # |
NP_542987 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_080797 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
DIDO1 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Yeast |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 92%; Dog: 92%; Guinea Pig: 86%; Horse: 92%; Human: 100%; Mouse: 92%; Rabbit: 100%; Rat: 92%; Yeast: 79% |
| Image 1 | Human Jurkat
 | WB Suggested Anti-DIDO1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: Jurkat cell lysateDIDO1 is strongly supported by BioGPS gene expression data to be expressed in Human Jurkat cells |
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