NFKBIB Antibody - N-terminal region (ARP34505_T100)

• Product Number: ARP34505_T100
• Name: NFKBIB Antibody - N-terminal region (ARP34505_T100)
• Protein Size (# AA): 356 amino acids
• Molecular Weight: 38kDa
• NCBI Gene Id: 4793
• Host: Rabbit
• Clonality: Polyclonal
• Concentration: 1.0 mg/ml
• Gene Full Name: Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
• Alias Symbols: IKBB, TRIP9
• Peptide Sequence: Synthetic peptide located within the following region: DLQNDLGQTALHLAAILGETSTVEKLYAAGAGLCVAERRGHTALHLACRVCA
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Reference: Lee,Y., et al., (2003) Mol. Hum. Reprod. 9 (4), 213-218
• Description of Target: Inhibition of NFkappa-B activity by the hepatitis C virus core protein might be related to its physical interaction with and interrupted nuclear localization of IKKbeta. Increased nuclear factor-kappaB (NF-kB) activity in the amnion during labor is associated with an increase in the expression of NF-kBp65 and of the NF-kB binding proteins IkBa, IkBb-1 and IkBb-2. IkappaBbeta may be a novel target for transcription factors of the HMG-box SRY/Sox family and imply a potential role for NF-kappaB/IkappaBbeta in spermatogenesis.
• Protein Interactions: VPS52; UBC; BAG3; TSPAN1; GIT2; RELA; REL; CSNK2A1; CDC25A; BAK1; APP; ZBTB7A; DNAJA3; IKBKB; CHUK; BRAP; IKBKG; TRE17; NFKBIA; NCOR2; PPARG; ESR2; POLR1D; POLR1E; POLR1A; POLR1C; POLR2H; NKIRAS2; POLR1B; NKIRAS1; LRPPRC; RASAL2; MTIF2; BTRC; CUL1; SKP1;
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Blocking Peptide: For anti-NFKBIB (ARP34505_T100) antibody is Catalog # AAP34505 (Previous Catalog # AAPY00527)
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human NFKBIB
• Uniprot ID: Q15653
• Protein Name: NF-kappa-B inhibitor beta
• Protein Accession #: NP_002494
• Purification: Protein A purified
• Nucleotide Accession #: NM_002503
• Tested Species Reactivity: Human, Mouse
• Gene Symbol: NFKBIB
• Predicted Species Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Yeast
• Application: WB
• Predicted Homology Based on Immunogen Sequence: Cow: 86%; Dog: 93%; Guinea Pig: 93%; Horse: 86%; Human: 100%; Mouse: 93%; Rabbit: 93%; Rat: 93%; Yeast: 91%
• Image 1: Human HepG2
  
  WB Suggested Anti-NFKBIB Antibody Titration: 1.25ug/ml
  ELISA Titer: 1:62500
  Positive Control: HepG2 cell lysate
• Image 2: Mouse Heart
  
  Host: Mouse
  Target Name: NFKBIB
  Sample Tissue: Mouse Heart
  Antibody Dilution: 1ug/ml