Product Number |
ARP34484_P050 |
Product Page |
www.avivasysbio.com/smarca2-antibody-middle-region-arp34484-p050.html |
Name |
SMARCA2 Antibody - middle region (ARP34484_P050) |
Protein Size (# AA) |
278 amino acids |
Molecular Weight |
32kDa |
NCBI Gene Id |
6595; 6597 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
0.5 mg/ml |
Gene Full Name |
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 and 4 |
Alias Symbols |
BRM, SNF2, SWI2, hBRM, NCBRS, Sth1p, BAF190, SNF2L2, SNF2LA, hSNF2a |
Peptide Sequence |
Synthetic peptide located within the following region: VINYKDSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKY |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reference |
Muchardt,C., et al., (1994) Mamm. Genome 5 (4), 241-242 |
Description of Target |
SMARCA2 is a member of the SWI/SNF family of proteins and is highly similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. Two transcript variants encoding different isoforms have been found for this gene, which contains a trinucleotide repeat (CAG) length polymorphism. |
Protein Interactions |
SDCBP; BEND7; UBC; SMURF2; EED; BMI1; SOX2; UL29; tat; SS18; SSX2; EPAS1; ARID1A; CBX5; PSMB2; ACTL6A; ARID1B; SEPT11; PHF10; NCOR1; SEC22B; SLC9A3R2; TOP2B; SMARCE1; SMARCD3; SMARCD2; SMARCD1; SMARCC2; SMARCC1; SMARCB1; SMARCA4; BMX; CEBPB; SIRT7; DPF1; |
Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Datasheets/Manuals |
Printable datasheet for anti-SMARCA2, SMARCA4 (ARP34484_P050) antibody |
Specificity |
100% homologous to both isoforms of SMARCA2 and all 5 isoforms of SMARCA4 |
Blocking Peptide |
For anti-SMARCA2, SMARCA4 (ARP34484_P050) antibody is Catalog # AAPY00506 |
Immunogen |
The immunogen is a synthetic peptide directed towards the middle region of human SMARCA2 |
Uniprot ID |
P51531, P51532 |
Purification |
Affinity Purified |
Tested Species Reactivity |
Human |
Gene Symbol |
SMARCA2 |
Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish |
Application |
WB, IHC |
Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100% |
Image 1 | Human Skin
| Human Skin |
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Image 2 | Human HepG2
| WB Suggested Anti-SMARCA2 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:312500 Positive Control: HepG2 cell lysate |
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