SMARCA2 Antibody - middle region (ARP34484_P050)

Data Sheet
 
Product Number ARP34484_P050
Product Page www.avivasysbio.com/smarca2-antibody-middle-region-arp34484-p050.html
Name SMARCA2 Antibody - middle region (ARP34484_P050)
Protein Size (# AA) 278 amino acids
Molecular Weight 32kDa
NCBI Gene Id 6595; 6597
Host Rabbit
Clonality Polyclonal
Concentration 0.5 mg/ml
Gene Full Name SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 and 4
Alias Symbols BRM, SNF2, SWI2, hBRM, NCBRS, Sth1p, BAF190, SNF2L2, SNF2LA, hSNF2a
Peptide Sequence Synthetic peptide located within the following region: VINYKDSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKY
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reference Muchardt,C., et al., (1994) Mamm. Genome 5 (4), 241-242
Description of Target SMARCA2 is a member of the SWI/SNF family of proteins and is highly similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. Two transcript variants encoding different isoforms have been found for this gene, which contains a trinucleotide repeat (CAG) length polymorphism.
Protein Interactions SDCBP; BEND7; UBC; SMURF2; EED; BMI1; SOX2; UL29; tat; SS18; SSX2; EPAS1; ARID1A; CBX5; PSMB2; ACTL6A; ARID1B; SEPT11; PHF10; NCOR1; SEC22B; SLC9A3R2; TOP2B; SMARCE1; SMARCD3; SMARCD2; SMARCD1; SMARCC2; SMARCC1; SMARCB1; SMARCA4; BMX; CEBPB; SIRT7; DPF1;
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for anti-SMARCA2, SMARCA4 (ARP34484_P050) antibody
Specificity 100% homologous to both isoforms of SMARCA2 and all 5 isoforms of SMARCA4
Blocking Peptide For anti-SMARCA2, SMARCA4 (ARP34484_P050) antibody is Catalog # AAPY00506
Immunogen The immunogen is a synthetic peptide directed towards the middle region of human SMARCA2
Uniprot ID P51531, P51532
Purification Affinity Purified
Tested Species Reactivity Human
Gene Symbol SMARCA2
Predicted Species Reactivity Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish
Application WB, IHC
Predicted Homology Based on Immunogen Sequence Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%
Image 1
Human Skin
Human Skin
Image 2
Human HepG2
WB Suggested Anti-SMARCA2 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: HepG2 cell lysate
 

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