| Product Number |
ARP34483_P050 |
| Product Page |
www.avivasysbio.com/egln2-antibody-n-terminal-region-arp34483-p050.html |
| Name |
EGLN2 Antibody - N-terminal region (ARP34483_P050) |
| Protein Size (# AA) |
407 amino acids |
| Molecular Weight |
44kDa |
| NCBI Gene Id |
112398 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
Egl nine homolog 2 (C. elegans) |
| Alias Symbols |
EIT6, PHD1, EIT-6, HPH-1, HPH-3, HIFPH1, HIF-PH1 |
| Peptide Sequence |
Synthetic peptide located within the following region: SAGSGTPRATATSTTASPLRDGFGGQDGGELRPLQSEGAAALVTKGCQRL |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Appelhoff,R.J., et al., (2004) J. Biol. Chem. 279 (37), 38458-38465 |
| Description of Target |
The hypoxia inducible factor (HIF) is a transcriptional complex which is involved in oxygen homeostasis. At normal oxygen levels, the alpha subunit of HIF is targeted for degration by prolyl hydroxylation. EGLN2 encodes an enzyme responsible for this posttranslational modification. Alternative splicing of EGLN2 results in three transcript variants encoding different isoforms. |
| Protein Interactions |
SRPK2; CEP192; IKBKG; FAM46A; EPAS1; A2M; MAGEA11; SIAH2; LPP; WTIP; AJUBA; LIMD1; TRIP6; SPRY2; PRPF19; EGLN3; EGLN2; HIF1A; HIF3A; MOB4; POLR2A; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-EGLN2 (ARP34483_P050) antibody |
| Blocking Peptide |
For anti-EGLN2 (ARP34483_P050) antibody is Catalog # AAP34483 (Previous Catalog # AAPY00505) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human EGLN2 |
| Uniprot ID |
Q96KS0 |
| Protein Name |
Egl nine homolog 2 |
| Protein Accession # |
NP_444274 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_053046 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
EGLN2 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Pig, Rabbit |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 79%; Dog: 93%; Guinea Pig: 86%; Human: 100%; Mouse: 93%; Pig: 93%; Rabbit: 79%; Rat: 93% |
| Image 1 | Human Placenta
 | WB Suggested Anti-EGLN2 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:1562500
Positive Control: Human Placenta |
|
