| Product Number |
ARP34463_T100 |
| Product Page |
www.avivasysbio.com/rrn3-antibody-middle-region-arp34463-t100.html |
| Name |
RRN3 Antibody - middle region (ARP34463_T100) |
| Protein Size (# AA) |
650 amino acids |
| Molecular Weight |
74kDa |
| NCBI Gene Id |
54700 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
1.0 mg/ml |
| Gene Full Name |
RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae) |
| Alias Symbols |
TIFIA, A-270G1.2 |
| Peptide Sequence |
Synthetic peptide located within the following region: VDGKVDNGKTKDLYRDLINIFDKLLLPTHASCHVQFFMFYLCSFKLGFAE |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Miller,G., et al., (2001) EMBO J. 20 (6), 1373-1382 |
| Description of Target |
In mammals, growth-dependent regulation of RNA polymerase I (Pol I) transcription is mediated by RRN3, an essential initiation factor. It interacts with Pol I in the absence of template DNA, augments Pol I transcription in vivo and rescues transcription in extracts from growth-arrested cells in vitro. |
| Protein Interactions |
UBC; ACTA1; Polr1e; POLR1B; EIF3L; NMI; RBM15; UBD; Trim28; ELAVL1; TAF1D; POLR1A; MYO1C; TAF1C; TAF1B; TAF1A; UBTF; TBP; PPP2R2A; CDK2; CCNE1; RIBIN; ACTB; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-RRN3 (ARP34463_T100) antibody |
| Blocking Peptide |
For anti-RRN3 (ARP34463_T100) antibody is Catalog # AAP34463 (Previous Catalog # AAPY00425) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the middle region of human RRN3 |
| Uniprot ID |
Q9NYV6 |
| Protein Name |
RNA polymerase I-specific transcription initiation factor RRN3 |
| Sample Type Confirmation |
RRN3 is supported by BioGPS gene expression data to be expressed in Jurkat |
| Protein Accession # |
NP_060897 |
| Purification |
Protein A purified |
| Nucleotide Accession # |
NM_018427 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
RRN3 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 86%; Dog: 93%; Guinea Pig: 86%; Horse: 86%; Human: 100%; Mouse: 86%; Rabbit: 86%; Rat: 100% |
| Image 1 | Human Jurkat
 | WB Suggested Anti-RRN3 Antibody Titration: 1.25ug/ml
ELISA Titer: 1:62500
Positive Control: Jurkat cell lysateRRN3 is supported by BioGPS gene expression data to be expressed in Jurkat |
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