APG4B Antibody - C-terminal region (ARP34434_P050)

Data Sheet
 
Product Number ARP34434_P050
Product Page www.avivasysbio.com/apg4b-antibody-c-terminal-region-arp34434-p050.html
Name APG4B Antibody - C-terminal region (ARP34434_P050)
Protein Size (# AA) 393 amino acids
Molecular Weight 44kDa
NCBI Gene Id 23192
Host Rabbit
Clonality Polyclonal
Concentration 0.5 mg/ml
Gene Full Name ATG4 autophagy related 4 homolog B (S. cerevisiae)
Alias Symbols APG4B, AUTL1
Peptide Sequence Synthetic peptide located within the following region: LGGALPMFELVELQPSHLACPDVLNLSLDSSDVERLERFFDSEDEDFEIL
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reference Tanida,I., et al., (2004) J. Biol. Chem. 279 (35), 36268-36276
Description of Target Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. APG4B encodes a member of the autophagin protein family and is also designated as a member of the C-54 family of cysteine proteases.
Protein Interactions SUMO2; MAP1LC3B; MAP1LC3A; BAG3; ATG8; YWHAB; GABARAPL1; SQSTM1; UBC; GABARAPL2; ATG10; ATG3; AMBRA1; GABARAP; CAMKK2; ATG12; ULK1; STK3; KRT4; ANXA1; FBXW11; LINC00341;
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for anti-ATG4B (ARP34434_P050) antibody
Blocking Peptide For anti-ATG4B (ARP34434_P050) antibody is Catalog # AAP34434 (Previous Catalog # AAPY00336)
Immunogen The immunogen is a synthetic peptide directed towards the C terminal region of human APG4B
Uniprot ID Q9Y4P1
Protein Name Cysteine protease ATG4B
Sample Type Confirmation

ATG4B is strongly supported by BioGPS gene expression data to be expressed in Raji

Protein Accession # NP_037457
Purification Affinity Purified
Nucleotide Accession # NM_013325
Tested Species Reactivity Human
Gene Symbol ATG4B
Predicted Species Reactivity Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish
Application IHC, WB
Predicted Homology Based on Immunogen Sequence Cow: 93%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 85%
Image 1
Human Raji
WB Suggested Anti-APG4B Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:12500
Positive Control: Raji cell lysateATG4B is strongly supported by BioGPS gene expression data to be expressed in Human Raji cells
Image 2
Human Lung
Rabbit Anti-ATG4B Antibody
Catalog Number: ARP34434
Paraffin Embedded Tissue: Human alveolar cell
Cellular Data: Epithelial cells of renal tubule
Antibody Concentration: 4.0-8.0 ug/ml
Magnification: 400X
Image 3
Human kidney
Human kidney
 

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