Product Number |
ARP34434_P050 |
Product Page |
www.avivasysbio.com/apg4b-antibody-c-terminal-region-arp34434-p050.html |
Name |
APG4B Antibody - C-terminal region (ARP34434_P050) |
Protein Size (# AA) |
393 amino acids |
Molecular Weight |
44kDa |
NCBI Gene Id |
23192 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
0.5 mg/ml |
Gene Full Name |
ATG4 autophagy related 4 homolog B (S. cerevisiae) |
Alias Symbols |
APG4B, AUTL1 |
Peptide Sequence |
Synthetic peptide located within the following region: LGGALPMFELVELQPSHLACPDVLNLSLDSSDVERLERFFDSEDEDFEIL |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reference |
Tanida,I., et al., (2004) J. Biol. Chem. 279 (35), 36268-36276 |
Description of Target |
Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. APG4B encodes a member of the autophagin protein family and is also designated as a member of the C-54 family of cysteine proteases. |
Protein Interactions |
SUMO2; MAP1LC3B; MAP1LC3A; BAG3; ATG8; YWHAB; GABARAPL1; SQSTM1; UBC; GABARAPL2; ATG10; ATG3; AMBRA1; GABARAP; CAMKK2; ATG12; ULK1; STK3; KRT4; ANXA1; FBXW11; LINC00341; |
Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Datasheets/Manuals |
Printable datasheet for anti-ATG4B (ARP34434_P050) antibody |
Blocking Peptide |
For anti-ATG4B (ARP34434_P050) antibody is Catalog # AAP34434 (Previous Catalog # AAPY00336) |
Immunogen |
The immunogen is a synthetic peptide directed towards the C terminal region of human APG4B |
Uniprot ID |
Q9Y4P1 |
Protein Name |
Cysteine protease ATG4B |
Sample Type Confirmation |
ATG4B is strongly supported by BioGPS gene expression data to be expressed in Raji |
Protein Accession # |
NP_037457 |
Purification |
Affinity Purified |
Nucleotide Accession # |
NM_013325 |
Tested Species Reactivity |
Human |
Gene Symbol |
ATG4B |
Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish |
Application |
IHC, WB |
Predicted Homology Based on Immunogen Sequence |
Cow: 93%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 85% |
Image 1 | Human Raji
| WB Suggested Anti-APG4B Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:12500 Positive Control: Raji cell lysateATG4B is strongly supported by BioGPS gene expression data to be expressed in Human Raji cells |
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Image 2 | Human Lung
| Rabbit Anti-ATG4B Antibody Catalog Number: ARP34434 Paraffin Embedded Tissue: Human alveolar cell Cellular Data: Epithelial cells of renal tubule Antibody Concentration: 4.0-8.0 ug/ml Magnification: 400X |
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Image 3 | Human kidney
| Human kidney |
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