Product Number |
ARP34429_T100 |
Product Page |
www.avivasysbio.com/nsd2-antibody-n-terminal-region-arp34429-t100.html |
Name |
NSD2 Antibody - N-terminal region (ARP34429_T100) |
Protein Size (# AA) |
310 amino acids |
Molecular Weight |
34kDa |
NCBI Gene Id |
7468 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
1.0 mg/ml |
Gene Full Name |
nuclear receptor binding SET domain protein 2 |
Alias Symbols |
WHS, TRX5, KMT3F, KMT3G, MMSET, WHSC1, REIIBP |
Peptide Sequence |
Synthetic peptide located within the following region: DPTSVAIASIQSAATFPDPNVKYVFRTENGGQVMYRVIQVSEGQLDGQTE |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reference |
Shoulders,C.C. et al., (2004) Nat. Genet. 36 (4), 322-323 |
Description of Target |
This gene encodes a protein that contains four domains present in other developmental proteins: a PWWP domain, an HMG box, a SET domain, and a PHD-type zinc finger. It is expressed ubiquitously in early development. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4. This gene maps to the 165 kb WHS critical region and has also been involved in the chromosomal translocation t(4;14)(p16.3;q32.3) in multiple myelomas. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. Some transcript variants are nonsense-mediated mRNA (NMD) decay candidates, hence not represented as reference sequences. |
Protein Interactions |
HIST1H3A; HIST3H3; HDAC1; TRIM28; UBC; SF3A1; HNRNPR; MPHOSPH10; RAD50; SART3; NUP93; GTF3C4; NOLC1; DDX21; BAZ1B; DDX18; KHSRP; RRP1; SMARCA5; SMC1A; RBM10; XRCC5; VIM; EZR; TOP2B; TOP1; TMPO; SMARCA4; SFPQ; RPN1; RBBP4; RANGAP1; PTBP1; PRKDC; PLRG1; PKP |
Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Datasheets/Manuals |
Printable datasheet for anti-NSD2 (ARP34429_T100) antibody |
Blocking Peptide |
For anti-NSD2 (ARP34429_T100) antibody is Catalog # AAP34429 (Previous Catalog # AAPY00331) |
Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human USF1 |
Uniprot ID |
P22415 |
Protein Name |
histone-lysine N-methyltransferase NSD2 |
Sample Type Confirmation |
WHSC1 is strongly supported by BioGPS gene expression data to be expressed in Jurkat |
Protein Accession # |
NP_009053 |
Purification |
Protein A purified |
Nucleotide Accession # |
NM_007122 |
Tested Species Reactivity |
Human |
Gene Symbol |
NSD2 |
Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit |
Application |
WB |
Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100% |
Image 1 | Human Jurkat
| WB Suggested Anti-USF1 Antibody Titration: 1.25ug/ml ELISA Titer: 1:312500 Positive Control: Jurkat cell lysateWHSC1 is strongly supported by BioGPS gene expression data to be expressed in Human Jurkat cells |
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