| Product Number |
ARP34289_P050 |
| Product Page |
www.avivasysbio.com/rnf2-antibody-middle-region-arp34289-p050.html |
| Name |
RNF2 Antibody - middle region (ARP34289_P050) |
| Protein Size (# AA) |
336 amino acids |
| Molecular Weight |
38kDa |
| NCBI Gene Id |
6045 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
Ring finger protein 2 |
| Alias Symbols |
BAP1, DING, BAP-1, HIPI3, RING2, RING1B |
| Peptide Sequence |
Synthetic peptide located within the following region: NASTHSNQEAGPSNKRTKTSDDSGLELDNNNAAMAIDPVMDGASEIELVF |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Voncken,J.W., et al., (2003) Proc. Natl. Acad. Sci. U.S.A. 100 (5), 2468-2473 |
| Description of Target |
Polycomb group (PcG) of proteins form the multiprotein complexes that are important for the transcription repression of various genes involved in development and cell proliferation. The protein encoded by RNF2 is one of the PcG proteins. It has been shown to interact with, and suppress the activity of, transcription factor CP2 (TFCP2/CP2). Studies of the mouse counterpart suggested the involvement of this gene in the specification of anterior-posterior axis, as well as in cell proliferation in early development. This protein was also found to interact with huntingtin interacting protein 2 (HIP2), an ubiquitin-conjugating enzyme, and possess ubiquitin ligase activity. |
| Protein Interactions |
BMI1; SCMH1; HIST2H2AC; UBE2D3; AMBRA1; WASH1; BECN1; ATG14; PIK3C3; TARDBP; SNAI1; NEDD8; UBC; EIF3I; ALYREF; RBM5; RCL1; TRIM28; CEBPZ; SUGP2; G3BP1; AKAP9; YAF2; LRPPRC; KIF20A; RAD50; ARPC4; ABCB6; SMC4; ACOT8; HNRNPDL; THOC1; THRAP3; RBM8A; KIAA0020; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-RNF2 (ARP34289_P050) antibody |
| Blocking Peptide |
For anti-RNF2 (ARP34289_P050) antibody is Catalog # AAP34289 (Previous Catalog # AAPP05639) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the middle region of human RNF2 |
| Uniprot ID |
Q99496 |
| Protein Name |
E3 ubiquitin-protein ligase RING2 |
| Sample Type Confirmation |
RNF2 is supported by BioGPS gene expression data to be expressed in Daudi |
| Protein Accession # |
NP_009143 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_007212 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
RNF2 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit, Zebrafish |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93% |
| Image 1 | Human Daudi
 | WB Suggested Anti-RNF2 antibody Titration: 1 ug/mL
Sample Type: Human Daudi |
|
| Image 2 | Human Heart
 | WB Suggested Anti-RNF2 antibody Titration: 1 ug/mL
Sample Type: Human Heart |
|
| Image 3 | Human Daudi
 | WB Suggested Anti-RNF2 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: Daudi cell lysateRNF2 is supported by BioGPS gene expression data to be expressed in Daudi |
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