BRD2 Antibody - middle region (ARP34212_P050)

• Product Number: ARP34212_P050
• Name: BRD2 Antibody - middle region (ARP34212_P050)
• Protein Size (# AA): 801 amino acids
• Molecular Weight: 88kDa
• NCBI Gene Id: 6046
• Host: Rabbit
• Clonality: Polyclonal
• Concentration: 0.5 mg/ml
• Gene Full Name: Bromodomain containing 2
• Alias Symbols: FSH, NAT, RNF3, FSRG1, RING3, D6S113E, O27.1.1, BRD2-IT1
• Peptide Sequence: Synthetic peptide located within the following region: QEQLRAVHEQLAALSQGPISKPKRKREKKEKKKKRKAEKHRGRAGADEDD
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Reference: Pal,D.K., et al., (2003) Am. J. Hum. Genet. 73 (2), 261-270
• Description of Target: BRD2 encodes a mitogen-activated kinase which localizes to the nucleus. BRD2 maps to the major histocompatability complex (MHC) class II region on chromosome 6p21.3 but sequence comparison suggests that the protein is not involved in the immune response. Homology to the Drosophila gene female sterile homeotic suggests that this human gene may be part of a signal transduction pathway involved in growth control.
• Protein Interactions: CSNK2A2; BRD7; ELAVL1; UBC; HIST1H4A; HIST2H2BE; TERF2; tat; TBP; E2F1; BRD2; HIST2H4A; HIST3H2BB; E2F2; RB1; KDM5A; RBL2;
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Blocking Peptide: For anti-BRD2 (ARP34212_P050) antibody is Catalog # AAP34212 (Previous Catalog # AAPP05527)
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human BRD2
• Uniprot ID: P25440
• Protein Name: Bromodomain-containing protein 2
• Sample Type Confirmation:

  BRD2 is strongly supported by BioGPS gene expression data to be expressed in Jurkat

• Protein Accession #: NP_005095
• Purification: Affinity Purified
• Nucleotide Accession #: NM_005104
• Tested Species Reactivity: Human
• Gene Symbol: BRD2
• Predicted Species Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Zebrafish
• Application: WB
• Predicted Homology Based on Immunogen Sequence: Cow: 100%; Dog: 100%; Guinea Pig: 86%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rat: 100%; Zebrafish: 92%
• Image 1: Human Jurkat
  
  WB Suggested Anti-BRD2 Antibody Titration: 0.2-1 ug/ml
  ELISA Titer: 1:62500
  Positive Control: Jurkat cell lysateBRD2 is strongly supported by BioGPS gene expression data to be expressed in Human Jurkat cells