| Product Number |
ARP34113_T100 |
| Product Page |
www.avivasysbio.com/ppara-antibody-middle-region-arp34113-t100.html |
| Name |
PPARA Antibody - middle region (ARP34113_T100) |
| Protein Size (# AA) |
468 amino acids |
| Molecular Weight |
51kDa |
| NCBI Gene Id |
5465 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
1.0 mg/ml |
| Gene Full Name |
Peroxisome proliferator-activated receptor alpha |
| Alias Symbols |
PPAR, NR1C1, hPPAR, PPARalpha, PPAR-alpha |
| Peptide Sequence |
Synthetic peptide located within the following region: IYEAYLKNFNMNKVKARVILSGKASNNPPFVIHDMETLCMAEKTLVAKLV |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
S, et al., (2004) Gastroenterology 127 (5), 1436-1445 |
| Description of Target |
Peroxisome proliferators include hypolipidemic drugs, herbicides, leukotriene antagonists, and plasticizers; this term arises because they induce an increase in the size and number of peroxisomes. Peroxisomes are subcellular organelles found in plants and animals which contain enzymes for respiration and for cholesterol and lipid metabolism. The action of peroxisome proliferators is thought to be mediated via specific receptors, called PPARs, which belong to the steroid hormone receptor superfamily. PPARs affect the expression of target genes involved in cell proliferation, cell differentiation and in immune and inflammation responses. Three closely related subtypes (alpha, beta/delta, and gamma) have been identified. This gene encodes the subtype PPAR-alpha, which is a nuclear transcription factor. |
| Protein Interactions |
SIRT1; PRMT1; PRMT8; RXRA; CHD9; NCOA1; FOXA3; CDK3; TNP1; HSP90AA1; NCOR2; NCOR1; SUMO1; UBE2I; LPIN1; SRC; TRA; MECR; STAC3; HELZ2; NRBF2; AIP; NR1H3; MED24; GADD45G; GADD45B; AKAP13; PPARGC1A; MED1; EP300; NRIP1; DAP3; MAPK3; DUT; RXRG; PRKCD; PRKCA; M |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-PPARA (ARP34113_T100) antibody |
| Blocking Peptide |
For anti-PPARA (ARP34113_T100) antibody is Catalog # AAP34113 (Previous Catalog # AAPP05586) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the middle region of human PPARA |
| Uniprot ID |
Q07869 |
| Protein Name |
Peroxisome proliferator-activated receptor alpha |
| Protein Accession # |
NP_005027 |
| Purification |
Protein A purified |
| Nucleotide Accession # |
NM_005036 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
PPARA |
| Predicted Species Reactivity |
Human, Mouse, Rat, Dog, Goat, Guinea Pig, Horse, Pig, Rabbit, Sheep |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Dog: 92%; Goat: 91%; Guinea Pig: 77%; Horse: 92%; Human: 100%; Mouse: 85%; Pig: 92%; Rabbit: 85%; Rat: 85%; Sheep: 91% |
| Image 1 | Human Jurkat
 | WB Suggested Anti-PPARA Antibody Titration: 2.5ug/ml
Positive Control: Jurkat cell lysate |
|
