Product Number |
ARP33993_P050 |
Product Page |
www.avivasysbio.com/cbfa2t3-antibody-n-terminal-region-arp33993-p050.html |
Name |
CBFA2T3 Antibody - N-terminal region (ARP33993_P050) |
Protein Size (# AA) |
567 amino acids |
Molecular Weight |
62kDa |
NCBI Gene Id |
863 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
0.5 mg/ml |
Gene Full Name |
Core-binding factor, runt domain, alpha subunit 2; translocated to, 3 |
Alias Symbols |
ETO2, MTG16, MTGR2, ZMYND4, RUNX1T3 |
Peptide Sequence |
Synthetic peptide located within the following region: QPRSTPPSMPPPPPAASQGATRPPSFTPHTLMNGSSHSPTAINGAPCTPN |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reference |
Powell,J.A., et al., (2002) Genomics 80 (3), 303-310 |
Description of Target |
The t(16;21)(q24;q22) translocation is a rare but recurrent chromosomal abnormality associated with therapy-related myeloid malignancies. The translocation produces a chimeric gene made up of the 5'-region of the AML1 gene fused to the 3'-region of CBFA2T3. In addition, CBFA2T3 is a putative breast tumor suppressor. |
Protein Interactions |
Zbtb38; Zbtb4; ZBTB33; GMEB2; SEC24A; MATN2; ZBTB47; UBC; RUNX1; TAL1; TRIM33; SIN3B; NCOR1; HDAC3; CBFA2T3; CBFA2T2; HDAC1; PRKAR2A; RUNX1T1; LDB1; TCF3; HDAC8; HDAC6; HDAC2; |
Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Datasheets/Manuals |
Printable datasheet for anti-CBFA2T3 (ARP33993_P050) antibody |
Blocking Peptide |
For anti-CBFA2T3 (ARP33993_P050) antibody is Catalog # AAP33993 (Previous Catalog # AAPP05068) |
Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human CBFA2T3 |
Uniprot ID |
O75082 |
Protein Name |
Protein CBFA2T3 |
Sample Type Confirmation |
CBFA2T3 is supported by BioGPS gene expression data to be expressed in Jurkat, MCF7 |
Protein Accession # |
NP_787127 |
Purification |
Affinity Purified |
Nucleotide Accession # |
NM_175931 |
Tested Species Reactivity |
Human |
Gene Symbol |
CBFA2T3 |
Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse |
Application |
WB |
Predicted Homology Based on Immunogen Sequence |
Cow: 92%; Dog: 92%; Guinea Pig: 100%; Horse: 85%; Human: 100%; Mouse: 100%; Rat: 100% |
Image 1 | Human Fetal Lung
| Host: Rabbit Target Name: CBFA2T3 Sample Tissue: Human Fetal Lung Antibody Dilution: 1.0ug/ml |
|
Image 2 | Human stomach, HepG2
| Host: Rabbit Target: CBFA2T3 Positive control (+): Human stomach (ST) Negative control (-): HepG2 (HG) Antibody concentration: 1ug/ml |
|