CBFA2T3 Antibody - N-terminal region (ARP33993_P050)

Data Sheet
 
Product Number ARP33993_P050
Product Page www.avivasysbio.com/cbfa2t3-antibody-n-terminal-region-arp33993-p050.html
Name CBFA2T3 Antibody - N-terminal region (ARP33993_P050)
Protein Size (# AA) 567 amino acids
Molecular Weight 62kDa
NCBI Gene Id 863
Host Rabbit
Clonality Polyclonal
Concentration 0.5 mg/ml
Gene Full Name Core-binding factor, runt domain, alpha subunit 2; translocated to, 3
Alias Symbols ETO2, MTG16, MTGR2, ZMYND4, RUNX1T3
Peptide Sequence Synthetic peptide located within the following region: QPRSTPPSMPPPPPAASQGATRPPSFTPHTLMNGSSHSPTAINGAPCTPN
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reference Powell,J.A., et al., (2002) Genomics 80 (3), 303-310
Description of Target The t(16;21)(q24;q22) translocation is a rare but recurrent chromosomal abnormality associated with therapy-related myeloid malignancies. The translocation produces a chimeric gene made up of the 5'-region of the AML1 gene fused to the 3'-region of CBFA2T3. In addition, CBFA2T3 is a putative breast tumor suppressor.
Protein Interactions Zbtb38; Zbtb4; ZBTB33; GMEB2; SEC24A; MATN2; ZBTB47; UBC; RUNX1; TAL1; TRIM33; SIN3B; NCOR1; HDAC3; CBFA2T3; CBFA2T2; HDAC1; PRKAR2A; RUNX1T1; LDB1; TCF3; HDAC8; HDAC6; HDAC2;
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for anti-CBFA2T3 (ARP33993_P050) antibody
Blocking Peptide For anti-CBFA2T3 (ARP33993_P050) antibody is Catalog # AAP33993 (Previous Catalog # AAPP05068)
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human CBFA2T3
Uniprot ID O75082
Protein Name Protein CBFA2T3
Sample Type Confirmation

CBFA2T3 is supported by BioGPS gene expression data to be expressed in Jurkat, MCF7

Protein Accession # NP_787127
Purification Affinity Purified
Nucleotide Accession # NM_175931
Tested Species Reactivity Human
Gene Symbol CBFA2T3
Predicted Species Reactivity Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse
Application WB
Predicted Homology Based on Immunogen Sequence Cow: 92%; Dog: 92%; Guinea Pig: 100%; Horse: 85%; Human: 100%; Mouse: 100%; Rat: 100%
Image 1
Human Fetal Lung
Host: Rabbit
Target Name: CBFA2T3
Sample Tissue: Human Fetal Lung
Antibody Dilution: 1.0ug/ml
Image 2
Human stomach, HepG2
Host: Rabbit
Target: CBFA2T3
Positive control (+): Human stomach (ST)
Negative control (-): HepG2 (HG)
Antibody concentration: 1ug/ml
 

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