| Product Number |
ARP33908_P050 |
| Product Page |
www.avivasysbio.com/kif3b-antibody-c-terminal-region-arp33908-p050.html |
| Name |
KIF3B Antibody - C-terminal region (ARP33908_P050) |
| Protein Size (# AA) |
747 amino acids |
| Molecular Weight |
85kDa |
| NCBI Gene Id |
142 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
Poly (ADP-ribose) polymerase 1 |
| Alias Symbols |
PARP, PPOL, ADPRT, ARTD1, ADPRT1, PARP-1, ADPRT 1, pADPRT-1 |
| Peptide Sequence |
Synthetic peptide located within the following region: APKVQAALDAALQDEDEIQVDASSFESTANKKSKARPKSGRKSGSSSSSS |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Jimbo,T., et al., (2002) Nat. Cell Biol. 4 (4), 323-327 |
| Description of Target |
The protein encoded by the KIF3B gene acts as a heterodimer with kinesin family member 3A to aid in chromosome movement during mitosis and meiosis. The encoded protein is a plus end-directed microtubule motor and can interact with the SMC3 subunit of the cohesin complex. In addition, the encoded protein may be involved in the intracellular movement of membranous organelles. This protein and kinesin family member 3A form the kinesin II subfamily of the kinesin superfamily. |
| Protein Interactions |
PARP1; CASP7; CASP3; UBE2I; TP53; SUMO2; CHFR; BANP; HUWE1; MDM2; SUMO3; DNMT1; CHD1L; IVNS1ABP; DDB2; PARP9; UBC; Rnf146; APLF; UHRF1; RPA3; RPA2; RPA1; ERG; MAFF; POLG2; RPL35; RPL27A; RPL19; RAD23A; PHB; CETN2; CETN1; DDX39A; PDLIM7; RPL14; MAFK; MAFG; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-PARP1 (ARP33908_P050) antibody |
| Blocking Peptide |
For anti-PARP1 (ARP33908_P050) antibody is Catalog # AAP33908 (Previous Catalog # AAPP04979) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the C terminal region of human KIF3B |
| Uniprot ID |
O15066 |
| Protein Name |
Kinesin-like protein KIF3B |
| Publications |
Weisschuh, N., Alavi, M. V, Bonin, M. & Wissinger, B. Identification of genes that are linked with optineurin expression using a combined RNAi--microarray approach. Exp. Eye Res. 85, 450-61 (2007). 17663987 |
| Protein Accession # |
NP_004789 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_004798 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
PARP1 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 92%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 92%; Rabbit: 100%; Rat: 100% |
| Image 1 | Human HepG2
 | WB Suggested Anti-KIF3B Antibody Titration: 0.2-1 ug/ml
Positive Control: HepG2 cell lysate |
|
