| Product Number |
ARP33354_P050 |
| Product Page |
www.avivasysbio.com/flj11730-antibody-n-terminal-region-arp33354-p050.html |
| Name |
FLJ11730 Antibody - N-terminal region (ARP33354_P050) |
| Protein Size (# AA) |
201 amino acids |
| Molecular Weight |
23kDa |
| NCBI Gene Id |
64769 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
MYST/Esa1-associated factor 6 |
| Alias Symbols |
EAF6, CENP-28, C1orf149, NY-SAR-91 |
| Peptide Sequence |
Synthetic peptide located within the following region: HNKAAPPQIPDTRRELAELVKRKQELAETLANLERQIYAFEGSYLEDTQM |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Lee,S.Y., et al., (2003) Proc. Natl. Acad. Sci. U.S.A. 100 (5), 2651-2656 |
| Description of Target |
The screening of cDNA expression libraries from human tumors with serum antibody (SEREX) has proven to be a powerful method for identifying the repertoire of tumor antigens recognized by the immune system of cancer patients, referred to as the cancer immunome. In this regard, cancer/testis (CT) antigens are of particular interest because of their immunogenicity and restricted expression patterns. Synoivial sarcomas are striking with regard to CT antigen expression, however, highly expressed in sarcoma, CT antigens do not induce frequent humoral immune responses in sarcoma patients. Sera from two patients were used to immunoscreen cDNA libraries from two synovial sarcoma cell lines and normal testis, resulting in the identification of 113 distinct antigens. Sarcoma antigen NY-SAR-91 is one of them. |
| Protein Interactions |
PLEKHF2; TRIM54; LDOC1; UBC; FXR2; H2AFZ; ELAVL1; SUMO2; JADE1; KAT5; tat; MRGBP; ING5; KAT6A; BRPF1; CCDC85B; L3MBTL2; ING3; ING4; KAT7; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-MEAF6 (ARP33354_P050) antibody |
| Blocking Peptide |
For anti-MEAF6 (ARP33354_P050) antibody is Catalog # AAP33354 (Previous Catalog # AAPP04396) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human FLJ11730 |
| Uniprot ID |
Q86WE3 |
| Protein Name |
Chromatin modification-related protein MEAF6 |
| Sample Type Confirmation |
MEAF6 is supported by BioGPS gene expression data to be expressed in Jurkat |
| Protein Accession # |
NP_073593 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_022756 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
MEAF6 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Zebrafish |
| Application |
IHC, WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Human: 100%; Mouse: 100%; Rat: 100%; Zebrafish: 92% |
| Image 1 | Human kidney
 | Human kidney |
|
| Image 2 | Human Jurkat
 | WB Suggested Anti-FLJ11730 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: Jurkat cell lysateMEAF6 is supported by BioGPS gene expression data to be expressed in Jurkat |
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