| Product Number |
ARP33352_P050 |
| Product Page |
www.avivasysbio.com/c20orf20-antibody-middle-region-arp33352-p050.html |
| Name |
C20ORF20 Antibody - middle region (ARP33352_P050) |
| Protein Size (# AA) |
204 amino acids |
| Molecular Weight |
22kDa |
| NCBI Gene Id |
55257 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
Chromosome 20 open reading frame 20 |
| Alias Symbols |
Eaf7, URCC4, MRG15BP, C20orf20 |
| Peptide Sequence |
Synthetic peptide located within the following region: LSTMYDMQALHESEILPFPNPERNFVLPEEIIQEVREGKVMIEEEMKEEM |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Cai,Y., (2003) J. Biol. Chem. 278 (44), 42733-42736 |
| Description of Target |
C20orf20 belongs to the EAF7 family. It is a component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage. |
| Protein Interactions |
MORF4L1; MORF4L2; NOTCH2NL; KRTAP10-7; H2AFZ; ELAVL1; SH3BP4; VAV2; UBC; H2AFV; MRFAP1; EPC1; DMAP1; MRGBP; MBTD1; EPC2; SIN3B; BRD8; RUVBL2; SRCAP; KAT5; RUVBL1; HIST2H2BE; TUBA1A; TUBB2A; RBBP7; HNRNPM; LMNA; KPNA2; KPNB1; HSPA4; HNRNPU; HNRNPK; ACTL6A; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-MRGBP (ARP33352_P050) antibody |
| Blocking Peptide |
For anti-MRGBP (ARP33352_P050) antibody is Catalog # AAP33352 (Previous Catalog # AAPP04394) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the middle region of human C20ORF20 |
| Uniprot ID |
Q9NV56 |
| Protein Name |
MRG-binding protein |
| Protein Accession # |
NP_060740 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_018270 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
MRGBP |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Zebrafish |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 93%; Dog: 93%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 93%; Rat: 100%; Zebrafish: 79% |
| Image 1 | Transfected 293T
 | WB Suggested Anti-C20ORF20 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: Transfected 293T |
|
