| Product Number |
ARP33321_P050 |
| Product Page |
www.avivasysbio.com/sox3-antibody-n-terminal-region-arp33321-p050.html |
| Name |
SOX3 Antibody - N-terminal region (ARP33321_P050) |
| Protein Size (# AA) |
446 amino acids |
| Molecular Weight |
45kDa |
| NCBI Gene Id |
6658 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
SRY (sex determining region Y)-box 3 |
| Alias Symbols |
PHP, GHDX, MRGH, PHPX, SOXB |
| Peptide Sequence |
Synthetic peptide located within the following region: LETELKNPVGTPTQAAGTGGPAAPGGAGKSSANAAGGANSGGGSSGGASG |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Raverot,G., et al., (2004) J. Clin. Endocrinol. Metab. 89 (8), 4146-4148 |
| Description of Target |
SOX3 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. Mutations in this gene have been associated with X-linked mental retardation with growth hormone deficiency. |
| Protein Interactions |
TRRAP; SUMO1; SUMO2; PAX6; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-SOX3 (ARP33321_P050) antibody |
| Blocking Peptide |
For anti-SOX3 (ARP33321_P050) antibody is Catalog # AAP33321 (Previous Catalog # AAPP04363) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human SOX3 |
| Uniprot ID |
P41225 |
| Protein Name |
Transcription factor SOX-3 |
| Sample Type Confirmation |
SOX3 is supported by BioGPS gene expression data to be expressed in Raji |
| Protein Accession # |
NP_005625 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_005634 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
SOX3 |
| Predicted Species Reactivity |
Human, Mouse, Dog, Pig, Rabbit |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Dog: 85%; Human: 100%; Mouse: 85%; Pig: 92%; Rabbit: 85% |
| Image 1 | Human heart
 | WB Suggested Anti-SOX3 antibody Titration: 1 ug/mL
Sample Type: Human heart |
|
| Image 2 | Human liver
 | WB Suggested Anti-SOX3 antibody Titration: 1 ug/mL
Sample Type: Human liver |
|
| Image 3 | Human Raji
 | WB Suggested Anti-SOX3 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:2500
Positive Control: Raji cell lysateSOX3 is supported by BioGPS gene expression data to be expressed in Raji |
|
