SOX4 Antibody - N-terminal region (ARP33252_P050)

• Product Number: ARP33252_P050
• Name: SOX4 Antibody - N-terminal region (ARP33252_P050)
• Protein Size (# AA): 474 amino acids
• Molecular Weight: 47kDa
• NCBI Gene Id: 6659
• Host: Rabbit
• Clonality: Polyclonal
• Concentration: 0.5 mg/ml
• Gene Full Name: SRY (sex determining region Y)-box 4
• Alias Symbols: CSS10, EVI16
• Peptide Sequence: Synthetic peptide located within the following region: MVQQTNNAENTEALLAGESSDSGAGLELGIASSPTPGSTASTGGKADDPS
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Reference: Hoser,M., (2007) J. Neurosci. 27 (20), 5495-5505
• Description of Target: SOX4 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. It may act as a transcriptional regulator after forming a protein complex with other proteins, such as syndecan binding protein (syntenin). The protein may function in the apoptosis pathway leading to cell death as well as to tumorigenesis and may mediate downstream effects of parathyroid hormone (PTH) and PTH-related protein (PTHrP) in bone development. The solution structure has been resolved for the HMG-box of a similar mouse protein. This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins, such as syndecan binding protein (syntenin). The protein may function in the apoptosis pathway leading to cell death as well as to tumorigenesis and may mediate downstream effects of parathyroid hormone (PTH) and PTH-related protein (PTHrP) in bone development. The solution structure has been resolved for the HMG-box of a similar mouse protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
• Protein Interactions: TAF5; UBE2I; ELAVL1; TP53; MDM2; EP300; tat; SDCBP;
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Additional Information: IHC Information: Human Testis (formalin-fixed, paraffin-embedded) stained with SOX4 antibody ARP33252_P050 followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.
• Blocking Peptide: For anti-SOX4 (ARP33252_P050) antibody is Catalog # AAP33252 (Previous Catalog # AAPP04290)
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SOX4
• Uniprot ID: Q06945
• Protein Name: Transcription factor SOX-4
• Protein Accession #: NP_003098
• Purification: Affinity Purified
• Nucleotide Accession #: NM_003107
• Tested Species Reactivity: Human
• Gene Symbol: SOX4
• Predicted Species Reactivity: Human, Mouse, Cow, Dog, Guinea Pig, Rabbit
• Application: IHC, WB
• Predicted Homology Based on Immunogen Sequence: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%
• Image 1: Human Testis
  
  Human Testis
• Image 2: Human Fetal Kidney
  
  Host: Rabbit
  Target Name: SOX4
  Sample Tissue: Human Fetal Kidney
  Antibody Dilution: 1.0ug/ml