RB1 Antibody - C-terminal region (ARP33212_P050)

Data Sheet
 
Product Number ARP33212_P050
Product Page www.avivasysbio.com/rb1-antibody-c-terminal-region-arp33212-p050.html
Name RB1 Antibody - C-terminal region (ARP33212_P050)
Protein Size (# AA) 928 amino acids
Molecular Weight 106kDa
NCBI Gene Id 5925
Host Rabbit
Clonality Polyclonal
Concentration 0.5 mg/ml
Gene Full Name Retinoblastoma 1
Alias Symbols RB, pRb, OSRC, pp110, p105-Rb, PPP1R130, p110-RB1
Peptide Sequence Synthetic peptide located within the following region: IMMCSMYGICKVKNIDLKFKIIVTAYKDLPHAVQETFKRVLIKEEEYDSI
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reference Dasgupta,P., et al., (2004) Mol. Cell. Biol. 24 (21), 9527-9541
Description of Target Retinoblastoma (RB) is an embryonic malignant neoplasm of retinal origin. It almost always presents in early childhood and is often bilateral. Spontaneous regression ('cure') occurs in some cases.
Protein Interactions RAF1; E2F1; ABL1; HDAC1; KDM2A; SMARCA4; USP7; UBC; DYRK1A; NEFM; DYRK1B; MAGEA11; ENC1; PPP1CA; CDKN1C; CDKN1A; CDK6; CDK4; CDK2; CCNE1; CCNA2; CCND1; HDAC11; PAX5; HIF1A; E2F4; CEBPE; CCNA1; SUMO1; UBE2I; TFAP2A; CDK3; CDK1; CCNC; CCNB1; MRPS18B; SUMO2;
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for anti-RB1 (ARP33212_P050) antibody
Blocking Peptide For anti-RB1 (ARP33212_P050) antibody is Catalog # AAP33212 (Previous Catalog # AAPP04249)
Immunogen The immunogen is a synthetic peptide directed towards the C terminal region of human RB1
Uniprot ID P06400
Protein Name Retinoblastoma-associated protein
Sample Type Confirmation

RB1 is strongly supported by BioGPS gene expression data to be expressed in Daudi

Protein Accession # NP_000312
Purification Affinity Purified
Nucleotide Accession # NM_000321
Tested Species Reactivity Human
Gene Symbol RB1
Predicted Species Reactivity Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish
Application WB
Predicted Homology Based on Immunogen Sequence Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 92%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%
Image 1
Human Daudi
WB Suggested Anti-RB1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: Daudi cell lysateRB1 is strongly supported by BioGPS gene expression data to be expressed in Human Daudi cells
 

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