Product Number |
ARP33212_P050 |
Product Page |
www.avivasysbio.com/rb1-antibody-c-terminal-region-arp33212-p050.html |
Name |
RB1 Antibody - C-terminal region (ARP33212_P050) |
Protein Size (# AA) |
928 amino acids |
Molecular Weight |
106kDa |
NCBI Gene Id |
5925 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
0.5 mg/ml |
Gene Full Name |
Retinoblastoma 1 |
Alias Symbols |
RB, pRb, OSRC, pp110, p105-Rb, PPP1R130, p110-RB1 |
Peptide Sequence |
Synthetic peptide located within the following region: IMMCSMYGICKVKNIDLKFKIIVTAYKDLPHAVQETFKRVLIKEEEYDSI |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reference |
Dasgupta,P., et al., (2004) Mol. Cell. Biol. 24 (21), 9527-9541 |
Description of Target |
Retinoblastoma (RB) is an embryonic malignant neoplasm of retinal origin. It almost always presents in early childhood and is often bilateral. Spontaneous regression ('cure') occurs in some cases. |
Protein Interactions |
RAF1; E2F1; ABL1; HDAC1; KDM2A; SMARCA4; USP7; UBC; DYRK1A; NEFM; DYRK1B; MAGEA11; ENC1; PPP1CA; CDKN1C; CDKN1A; CDK6; CDK4; CDK2; CCNE1; CCNA2; CCND1; HDAC11; PAX5; HIF1A; E2F4; CEBPE; CCNA1; SUMO1; UBE2I; TFAP2A; CDK3; CDK1; CCNC; CCNB1; MRPS18B; SUMO2; |
Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Datasheets/Manuals |
Printable datasheet for anti-RB1 (ARP33212_P050) antibody |
Blocking Peptide |
For anti-RB1 (ARP33212_P050) antibody is Catalog # AAP33212 (Previous Catalog # AAPP04249) |
Immunogen |
The immunogen is a synthetic peptide directed towards the C terminal region of human RB1 |
Uniprot ID |
P06400 |
Protein Name |
Retinoblastoma-associated protein |
Sample Type Confirmation |
RB1 is strongly supported by BioGPS gene expression data to be expressed in Daudi |
Protein Accession # |
NP_000312 |
Purification |
Affinity Purified |
Nucleotide Accession # |
NM_000321 |
Tested Species Reactivity |
Human |
Gene Symbol |
RB1 |
Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish |
Application |
WB |
Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 92%; Rabbit: 100%; Rat: 100%; Zebrafish: 100% |
Image 1 | Human Daudi
| WB Suggested Anti-RB1 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:312500 Positive Control: Daudi cell lysateRB1 is strongly supported by BioGPS gene expression data to be expressed in Human Daudi cells |
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